Determination of lacidipine in human plasma by LC-MS/MS: Application in a bioequivalence study

H Chen, L Li, S Song, Y Du, X Jin… - … Pharmacology and …, 2018 - search.proquest.com
… quantification of lacidipine in human … for lacidipine and m/z 389.2 → 315.0 for IS, respectively.
Then, the established method was applied in a bioequivalence study comparing lacidipine

[HTML][HTML] Virtual population pharmacokinetic using physiologically based pharmacokinetic model for evaluating bioequivalence of oral lacidipine formulations in dogs

B Yang, C Wu, B Ji, M Wu, Z He, L Shang… - asian journal of …, 2017 - Elsevier
… model for evaluating bioequivalence of oral lacidipine formulations in dogs. The dissolution
behaviors of three lacidipine formulations including one … Clinical pharmacology of lacidipine

ANTI-INFLAMMATORY, ANALGESIC, AND GASTRIC TISSUE EFFECTS OF LACIDIPINE, ASPIRIN, AND THEIR COMBINATION

B IŞIK, İ ATEŞ, B SÜLEYMAN… - Acta Poloniae …, 2023 - avesis.ebyu.edu.tr
Lacidipine, a calcium channel blocker, can protect gastric tissue from aspirin-induced …
analgesic, and gastric tissue effects of using lacidipine and aspirin in combination and separately. (…

[PDF][PDF] Beneficial effects of combined therapy with lacidipine and candesartan in obese hypertensive patients

T Ashcheulova, N Gerasimchuk, O Kovalyova… - Romanian Journal of …, 2018 - sciendo.com
… antihypertensive therapy with lacidipine and candesartan on … and angiotensin receptor
blocker (lacidipine 2 mg, 4 mg, and … antihypertensive therapy with lacidipine and candesartan, a …

Lacidipine attenuates symptoms of nicotine withdrawal in mice

K Khurana, M Kumar, N Bansal - Neurotoxicity Research, 2021 - Springer
… The present study is aimed to explore the effects of lacidipine … , tid) from days 1 to 7 and
alongside lacidipine (0.3, 1, and 3 mg/… subjected to nicotine-withdrawal and lacidipine (3 mg/kg) …

[PDF][PDF] … DEVELOPMENT AND VALIDATION FOR THE IMPURITY RELATED TO THE ESTIMATION PROCESS FROM LACIDIPINE BULK AND FORMULATION

DS Musmade, PB Gaikwad, S Desai, BH Garje… - lcebyhkzz.cn
… in the formulation of lacidipine, a 100ml stock solution of lacidipine hydrochloride was
prepared. For the purpose of quantifying the intermediate in the lacidipine formulation, 4 ml of …

Lacidipine attenuates reserpine-induced depression-like behavior and oxido-nitrosative stress in mice

K Khurana, N Bansal - Naunyn-Schmiedeberg's archives of pharmacology, 2019 - Springer
lacidipine (LCD), L-type Ca 2+ -channel blocker, on reserpine-induced depression in mice.
Separate groups of mice (Swiss albino, 18–25 g) were administered lacidipine … that lacidipine

[HTML][HTML] Selection of antihypertensive drugs from the perspective of clinical pharmacology

G Victor, B Nicolae, P Lilia, T Lucia… - The Moldovan Medical …, 2018 - cyberleninka.ru
… The medicine data based on available and currently known evidences in the field of clinical
pharmacology allow determination of the principles of selection and assessment of the use …

[HTML][HTML] A novel high content angiogenesis assay reveals that Lacidipine, L-type calcium channel blocker, induces in vitro vascular lumen expansion

DA Nawrot, LY Ozer, A Al Haj Zen - International Journal of Molecular …, 2022 - mdpi.com
… cells treated with Lacidipine showed enhanced activity of caspase-3 in the luminal space.
Pharmacological inhibition of caspase activity abolished the Lacidipine-enhancing effect on …

Lacidipine prevents scopolamine-induced memory impairment by reducing brain oxido-nitrosative stress in mice

K Khurana, M Kumar, N Bansal - Neurotoxicity research, 2021 - Springer
lacidipine-induced improvement in memory and redox balance in scopolamine-administered
mice. Lacidipine … These properties of lacidipine can mitigate the pathogenesis of AD-type …