Antifungal agents: spectrum of activity, pharmacology, and clinical indications
… The currently available antifungal agents vary significantly in terms of spectrum of activity.
The echinocandins exhibit potent activity against Candida, whereas the newer triazoles offer …
The echinocandins exhibit potent activity against Candida, whereas the newer triazoles offer …
[HTML][HTML] Adverse effects associated with currently commonly used antifungal agents: A network meta-analysis and systematic review
YL Yang, ZJ Xiang, JH Yang, WJ Wang… - … in Pharmacology, 2021 - frontiersin.org
… of AEs associated with nine commonly used antifungal agents was conducted. A total of …
antifungal agent tolerability, clinical AEs and laboratory AEs. Meanwhile, a subgroup analysis …
antifungal agent tolerability, clinical AEs and laboratory AEs. Meanwhile, a subgroup analysis …
Antifungals in clinical use and the pipeline
MD Johnson - Infectious Disease Clinics, 2021 - id.theclinics.com
… The ideal antifungal agent in regard to spectrum of activity, pharmacokinetic/… This article
reviews pharmacologic aspects of currently available systemic antifungal agents in use for …
reviews pharmacologic aspects of currently available systemic antifungal agents in use for …
Antifungal agents and the kidney: pharmacokinetics, clinical nephrotoxicity, and interactions
A Tragiannidis, A Gkampeta, M Vousvouki… - Expert opinion on …, 2021 - Taylor & Francis
… A detailed analysis of various trials and a larger number of meta-analyses concluded that …
appropriate, polyene antifungal agents may be avoided and alternative agents may be used, …
appropriate, polyene antifungal agents may be avoided and alternative agents may be used, …
Administration and dosing of systemic antifungal agents in pediatric patients
… of antifungals in children are limited. This paper reviews the spectra of activity for approved
antifungal agents … regarding the current state of antifungal clinical pharmacology in pediatrics. …
antifungal agents … regarding the current state of antifungal clinical pharmacology in pediatrics. …
Clinical hepatotoxicity associated with antifungal agents
I Kyriakidis, A Tragiannidis, S Munchen… - Expert opinion on drug …, 2017 - Taylor & Francis
… This article reviews current data on drug-induced hepatotoxicity of antifungal agents used
for … pharmacological interventions, a thorough understanding of hepatic adverse effects of …
for … pharmacological interventions, a thorough understanding of hepatic adverse effects of …
Pharmacokinetics–pharmacodynamics of antifungal agents in the central nervous system
… preclinical and clinical data that quantify antifungal pharmacokinetics (… clinical use of existing
antifungal drugs, and introduces novel … and use of antifungal drugs for CNS fungal disease. …
antifungal drugs, and introduces novel … and use of antifungal drugs for CNS fungal disease. …
[PDF][PDF] Building a clinical pharmacology framework for the safe and effective use of antifungal agents
VJC Lempers - 2016 - repository.ubn.ru.nl
… antifungal agents Despite research that has been conducted in the field of clinical pharmacology
of antifungal drugs, … of the clinical pharmacology of antifungal drugs in order to optimize …
of antifungal drugs, … of the clinical pharmacology of antifungal drugs in order to optimize …
[HTML][HTML] Antifungals: From Pharmacokinetics to Clinical Practice
… In addition to the pharmacological properties of the antifungal drugs, our review also … in
order to be aware of the existence of antifungal resistance. The adequate knowledge of the …
order to be aware of the existence of antifungal resistance. The adequate knowledge of the …
Therapeutic drug monitoring of systemic antifungal agents: a pragmatic approach for adult and pediatric patients
J John, A Loo, S Mazur, TJ Walsh - Expert opinion on drug …, 2019 - Taylor & Francis
… considerations for TDM of select antifungal agents. The objective of this review is to describe
the rationale for TDM, … General clinical pharmacology considerations for pediatric studies for …
the rationale for TDM, … General clinical pharmacology considerations for pediatric studies for …