[HTML][HTML] Pias1 is essential for erythroid and vascular development in the mouse embryo

JD Constanzo, M Deng, S Rindhe, K Tang… - Developmental …, 2016 - Elsevier
yolk sac (YS) blood islands approximately at embryonic (E) days 7.5–8.5. These nucleated
red blood cells begin circulating the embryo … This analysis revealed that Pias1 null embryonic …

[HTML][HTML] Interaction of the macrophage and primitive erythroid lineages in the mammalian embryo

J Palis - Frontiers in immunology, 2017 - frontiersin.org
… numbers within the yolk sac of the mouse embryo beginning at … erythroblastic islands from
E14.5 fetal livers also revealed late-… Clonal analysis identifies hemogenic endothelium as the …

[HTML][HTML] Embryonic origins of the hematopoietic system: hierarchies and heterogeneity

CS Vink, SA Mariani, E Dzierzak - Hemasphere, 2022 - journals.lww.com
Clonal transplantation analyses revealed the heterogeneity … at mouse embryonic day (E)7.5
in the YS blood islands with … hemangioblastic chords containing polyclonal cells with …

Myeloid cell origins, differentiation, and clinical implications

K Weiskopf, PJ Schnorr, WW Pang… - Myeloid Cells in …, 2017 - Wiley Online Library
… ES cell into uncolored mouse blastocysts; the yolk sac blood islands of these mice rarely
contained … Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood

Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers

JM Tsai, R Sinha, J Seita, N Fernhoff, S Christ… - Science translational …, 2018 - science.org
… the lack of an identifiable cell of origin. Using clonal analysis and lineage tracing, we have
… mesothelial cells from injured mesothelium revealed aspects of the pathological mechanism …

[HTML][HTML] Primitive erythrocytes are generated from hemogenic endothelial cells

M Stefanska, K Batta, R Patel, M Florkowska… - Scientific reports, 2017 - nature.com
murine embryogenesis, primitive erythroid (Ery/P) progenitors appear in the yolk sac blood
islands … potential, the results obtained with ES cells, and notably the presence of clonal blast …

[HTML][HTML] Intestinal cancer stem cells marked by Bmi1 or Lgr5 expression contribute to tumor propagation via clonal expansion

H Yanai, N Atsumi, T Tanaka, N Nakamura, Y Komai… - Scientific Reports, 2017 - nature.com
Clonal analysis using ubiquitous multicolor lineage tracing revealed that colon tumors …
that the polyclonal origin of colon tumors is just not detected because the models used in this …

The role of Runx1 in embryonic blood cell formation

AD Yzaguirre, MFTR de Bruijn, NA Speck - RUNX proteins in development …, 2017 - Springer
… In vivo clonal analyses provided further evidence against the … blood island (VBI), which is
analogous to mouse yolk sac … the embryo proper between E10.5 and E11.5 has revealed that …

Identification of a mesodermal progenitor for the pro-definitive angio-hematopoietic lineage

T Lazarov, PL Loyher, H Yang, ZN Choo, Z Deng… - bioRxiv, 2024 - biorxiv.org
… We report here the identification in mouse gastrula and human (h)iPSC cultures of a …
Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands

[HTML][HTML] Hematopoiesis: a layered organization across chordate species

R Elsaid, F Soares-da-Silva, M Peixoto… - … and Developmental …, 2020 - frontiersin.org
revealed that the first blood cells appear in the yolk sac (YS): … an endothelial layer, named
blood islands. The order of events … , mice, and humans) were the first where the distinct origins