[HTML][HTML] The C and E subunits of the serotonin 5-HT3 receptor subtly modulate electrical properties of the receptor

NS Yaakob, DT Nguyen, B Exintaris… - Biomedicine & …, 2018 - Elsevier
Serotonin type 3 (5-hydroxytrptamine-3, 5-HT 3 ) receptors are ligand-gated cation channels
present in both central and peripheral nervous systems. In humans there are five different …

[HTML][HTML] Visualising functional 5-HT3 receptors containing A and C subunits at or near the cell surface

IPL Abad, RL Fam, DT Nguyen, CJ Nowell… - Biomedicine & …, 2020 - Elsevier
… subunits of the human serotonin 3 (5-… cloning [45] was used to incorporate the fluorescent
proteins, eGFP and m-Cherry, between the third and fourth transmembrane region in human 5-…

Tapping into 5-HT3 Receptors to Modify Metabolic and Immune Responses

H Irving, I Turek, C Kettle, N Yaakob - International Journal of Molecular …, 2021 - mdpi.com
serotonin-induced skin itch [131] and neuraxial opioid-induced pruritus [132]. Direct irradiation
cell death evoked by serotonin … No new data were created or analyzed in this study. Data …

Phylogenetic analyses of 5-hydroxytryptamine 3 (5-HT3) receptors in Metazoa

STRB Rao, I Turek, HR Irving - Plos one, 2023 - journals.plos.org
… only pentameric ligand gated ion channel among the serotonin receptors. 5-HT 3 receptors
… 3 receptor subunit, 5-HT 3 receptor-like subunit, unnamed, hypothetical, and uncharacterized …

Delineating the Site of Interaction of the 5-HT3A Receptor with the Chaperone Protein RIC-3

E Pirayesh, AG Stuebler, A Pandhare, M Jansen - Biophysical Journal, 2020 - cell.com
… the intracellular domain of serotonin channels mediates this effect. … hRIC-3 was cloned into
the prokaryotic expression vector … ion channels: functional 5-HT3 and GABA rho1 receptors …

Cryo-EM structure of 5-HT3A receptor in its resting conformation

S Basak, Y Gicheru, A Samanta, SK Molugu… - Nature …, 2018 - nature.com
… The full-length mouse 5-HT 3A R was cloned into an oocyte expression vector for
functional measurements. In response to application of serotonin, robust concentration-dependent …

Evolução molecular do receptor serotoninérgico 5-HT3 em primatas do novo mundo e outros cordados

G Reales Monteagudo - 2018 - lume.ufrgs.br
… Interestingly, comparative expression analyses in humans revealed different expression
The 5-HT3 serotonin binding pocket is similar to that of acetylcholine in the nAChR, in that …

5-HT3 Receptors on Mitochondria Influence Mitochondrial Function

STRB Rao, I Turek, J Ratcliffe, S Beckham… - International Journal of …, 2023 - mdpi.com
expressing cells upon serotonin exposure during the monitoring period. However, subunit-E-expressing
containing mCherry via the Gibson cloning procedure as previously described, …

5-HT3 receptors

L Zhang, SCR Lummis - Allosteric Receptor Modulation in Drug …, 2016 - taylorfrancis.com
… The subsequent cloning of complementary DNA (cDNA) encoding 5-HT3 receptor sub…
Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like

Regulation of the Serotonin 2a Receptor Encoding Gene Htr2a by Early Growth Response Gene 3 (Egr3)

X Zhao - 2017 - keep.lib.asu.edu
… To determine the functionality of this binding, I co-transfected the CMV-EGR3 vector or
CMV-vector alone with the Htr2a distal promoter reporter clone. I found overexpression of EGR3 …