The translational landscape of human vascular smooth muscle cells identifies novel short open reading frame-encoded peptide regulators for phenotype alteration

K Li, B Li, D Zhang, T Du, H Zhou, G Dai… - Cardiovascular …, 2023 - academic.oup.com
… and cloned into pCFH-3×FLAG or phage-6tag vector. A mutant plasmid was generated by …
differentially translating RNA transcripts in this study regulated the alteration VSMC phenotype

Nuclear control of vascular smooth muscle cell plasticity during vascular remodeling

IA Ahmed, M Liu, D Gomez - The American Journal of Pathology, 2024 - Elsevier
… role in regulating SMC functions and phenotypic transitions during vascular remodeling
and … behaviors of SMCs that contribute to the etiology of cardiovascular diseases differently. …

Genetic regulation of atherosclerosis-relevant phenotypes in human vascular smooth muscle cells

R Aherrahrou, L Guo, VP Nagraj, A Aguhob… - Circulation …, 2020 - Am Heart Assoc
… Cells isolated from each individual responded differently to cytokine stimulation. For … It is
also possible that more proliferative SMC clones in the isolated cell population have gained …

Transforming growth factor β1 suppresses proinflammatory gene program independent of its regulation on vascular smooth muscle differentiation and autophagy

P Gao, W Wu, J Ye, YW Lu, AP Adam, HA Singer… - Cellular signalling, 2018 - Elsevier
… Compared with the well-recognized role of VSMC phenotypic modulation in vascular
pathologies, the hierarchical regulation among different gene programs during VSMC phenotypic

Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: novel targets for therapy

LM Khachigian, BL Black, P Ferdinandy… - Vascular …, 2022 - Elsevier
regulatory mechanisms governing SMC phenotypicdifferentially expressed in murine and
human atherosclerotic lesions [90] and undergoes phosphorylation at Ser26, which regulates

Vascular smooth muscle

LL Hilenski, K Griendling - Vascular Medicine: A Companion to …, 2019 - books.google.com
… –like contractile phenotype because conversion of cells to a VSMC… genes. 58 These
differential pathways provide a switch in which SRF target genes are differentially regulated through

[HTML][HTML] Gax regulates human vascular smooth muscle cell phenotypic modulation and vascular remodeling

H Zheng, Z Hu, X Zhai, Y Wang, J Liu… - American Journal of …, 2016 - ncbi.nlm.nih.gov
cloned to lentiviral expression vector pLenti6.3-IRES-EGFP by recombinant DNA technology.
The positive clones … hierarchical clustering of differentially expressed genes in HASMCs …

Vascular smooth muscle cell

N Zhou, S Stoll, C Leimena, H Qiu - Muscle Cell and Tissue …, 2018 - books.google.com
through the different approaches:(1) identifying genes/proteins targets that differentially
regulate VSMC phenotype changes … of synthetic phenotype;(2) identifying genes/proteins that …

[PDF][PDF] H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity

M Liu, C Espinosa-Diez, S Mahan, M Du, AT Nguyen… - Developmental cell, 2021 - cell.com
Vascular smooth muscle cells (SMCs) are specialized contractile cells that retain phenotypic
… (A) Volcano plot representing genes differentially expressed in Myocd-LSD1 versus Myocd-…

… of induced pluripotent stem cell-derived vascular endothelial and smooth muscle cells in coculture to hemodynamics induces primary vascular cell-like phenotypes

MS Collado, BK Cole, RA Figler… - Stem cells …, 2017 - academic.oup.com
… into vascular endothelial (iEC) and smooth muscle (iSMC) … an intact blood vessel, they
represent an immature phenotype. … important roles in vascular cell phenotypic modulation. Here …