… Clostridium botulinum C3 is the prototype of C3-like ADP-ribosyltransferases that selectively
ADP-ribosylate the small GTP-binding proteins RhoA/B/C … tool to study cellular Rho functions…

… of Clostridium botulinum C3 exoenzyme (C3bot) in two cell lines. Here, we used primary
neuronal cultures from vimentin knockout (Vim −/− ) mice to study … mediated by Rho proteins. In …

… on avian and mammalian rho subfamily proteins by its active … for studying the cellular
contribution of rho subfamily proteins … to glutamate of Clostridium limosum exoenzyme C3 turns …

… The Rho ADP-ribosylating C3 exoenzyme (C3bot) is a bacterial protein toxin devoid of a
cell-binding or -translocation domain. … However, we and others have shown that C3 from C. …

… C3 is a 24 kDa single-chain protein, belongs to the family of … In this study, the effect of different
constructs of C3 on SGN alone … of the C3 exoenzyme derived from Clostridium botulinum …

… Thus, biological effects by C3 exoenzyme described in this … of rho proteins and not that
of rac proteins. Furthermore, … G protein rhoC is ADP-ribosylated by Clostridium botulinum …

… C3 exoenzyme from Clostridium botulinum (C3) belongs to the … on the transcriptional level
and downstream proteins in HT22 … We demonstrated that C3 Rho-dependently modulated the …

… C3 exoenzyme transferase from Clostridium botulinum is a toxin that causes the specific
ADP-ribosylation of Rho-like proteins, … this study; FLF supervised and designed the study; YTM, …

… Clostridium botulinum C3 exoenzyme (C3bot) exclusively … expressed as recombinant
GST-fusion proteins in E. coli TG1 … Accessibility of intracellular Rho of the skin model to C3 was …

… the C3 protein toxins (~25 kDa) from Clostridium (C.) botulinum (… proof-of-concept in this
study, for further in vivo studies, the production … effects of Clostridium botulinum C3 exoenzyme. J …