Drug-loaded implantable surgical cavity-adaptive hydrogels for prevention of local tumor recurrence

B Zhuang, T Chen, Z Xiao, Y Jin - International journal of pharmaceutics, 2020 - Elsevier
… locally implanted dual drug-loaded cavity-adaptive hydrogel … in situ forming hydrogel as a
post-breast tumor resection implant. … pieces of hydrogels, including yellow and blue hydrogels, …

Codelivery of paclitaxel and temozolomide through a photopolymerizable hydrogel prevents glioblastoma recurrence after surgical resection

M Zhao, E Bozzato, N Joudiou, S Ghiassinejad… - Journal of controlled …, 2019 - Elsevier
… ) within a hydrogel to synergistically inhibit tumor growth. The … PEG-DMA hydrogel implanted
group (n = 5); resection, PTX … (green) PEG-DMA hydrogels containing PLGA-NPs in healthy …

[HTML][HTML] Gold nanorods and nanohydroxyapatite hybrid hydrogel for preventing bone tumor recurrence via postoperative photothermal therapy and bone regeneration …

J Liao, K Shi, Y Jia, Y Wu, Z Qian - Bioactive materials, 2021 - Elsevier
… caused by the surgical resection of bone tumor (Scheme 1B). … hydrogel was then implanted
for photothermal treatment to … of the residual bone tumor containing hybrid hydrogel quickly …

Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model

J Conde, N Oliva, Y Zhang, N Artzi - Nature materials, 2016 - nature.com
… as a prophylactic hydrogel patch to prevent cancerhydrogel containing both drug–gold
nanorods and siRNA–gold nanospheres was implanted on top of the tumour before its resection

[HTML][HTML] Photothermal hydrogel platform for prevention of post-surgical tumor recurrence and improving breast reconstruction

X Yang, L Gao, Y Wei, B Tan, Y Wu, C Yi… - Journal of …, 2021 - Springer
… of the syringe and the implantation of the materials, which was a … removal; c The hydrogel
platform was injected into the tumor … cavity after breast surgery, and the contained porous MPs …

… hydrogel implant combining chemotherapy and tumor microenvironment remodeling for preventing postoperative recurrence and metastasis of breast cancer

J Li, Q Chen, S Li, X Zeng, J Qin, X Li, Z Chen… - Chemical Engineering …, 2023 - Elsevier
implantation into the tumor surgical cavity, DOX/Met@HDP persistently retains drugs at the
tumor resection sites and releases drugs in a tumor … HDP hydrogels in 200 μL PBS containing

[HTML][HTML] … of 5-fluorouracil and cis-platinum via biodegradable thermo-sensitive hydrogel for intraoperative synergistic combination chemotherapy of gastric cancer

W Chen, K Shi, J Liu, P Yang, R Han, M Pan, L Yuan… - Bioactive materials, 2023 - Elsevier
… gastric cancer, the curative effect of surgical resection is … the need for invasive surgery and
implantation procedures [27,28]. … Notably, the inserts containing hydrogel were kept at 37 C for …

Combination therapy of killing diseases by injectable hydrogels: from concept to medical applications

F Poustchi, H Amani, Z Ahmadian… - Advanced …, 2021 - Wiley Online Library
… while killing cancer cells after surgical cancer tissue resection. [ … the injection of the hydrogel
containing the two drug cocktail … injectable chemo-radio-hydrogel implants can be served as …

Inhibition of tumor recurrence and metastasis via a surgical tumor-derived personalized hydrogel vaccine

Y Lu, C Wu, Y Yang, X Chen, F Ge, J Wang… - Biomaterials …, 2022 - pubs.rsc.org
… This combination therapy strategy could effectively inhibit the … , we implanted the hydrogels
during the surgical removal of … Each hydrogel contained 1 μg of GM-CSF or 0.1 mg of tumor

Advances and trends of hydrogel therapy platform in localized tumor treatment: A review

B Tan, L Huang, Y Wu, J Liao - Journal of Biomedical Materials …, 2021 - Wiley Online Library
… Such as the PEGDA hydrogel containing methylene blue … in surgical resection and GemC
12 -LNC hydrogel implantation … of combined therapy in clinical GBM after treatment regimen. …