1. Sexual arousal→ release of nitric oxide (NO) at nerve endings of the penis. Another source
of NO is in the vascular endothelial cells. 2. NO diffuses into vascular smooth muscle cells …

… 1 week prior to erectile function testing and sildenafil (0.3 mg/… Interestingly, the combined
effect of sildenafil and BTX-A was … When combined with sildenafil, 32 guanethidine ic has been …

… : β-blocker or verapamil monotherapy, the combination of a … warning against the combined
use with guanethidine due to … of orthostatic hypotension and erectile dysfunction with impaired …

… such as propranolol are more likely to cause sexual dysfunction, … 20 Sildenafil is an oral
fast-absorbing drug for erectile … Citation63 The combination of erectile dysfunction with obesity …

… with methyldopa than with guanethidine or ganglionic blocking … Topically administration
guanethidine enhances response of … action of guanethidine, allowing dose of guanethidine to be …

… agents (such as guanethidine and guanadrel), thereby … Sildenafil was initially developed
as an antianginal, but its … calcium channel blockers such as verapamil or diltiazem is not …

… Bethanidine, guanethidine, and debrisoquin are selective … by sildenafil and related
compounds (see later discussion). … If verapamil is given in combination with a β blocker, patients …

… Moreover, when combined with sildenafil, guanethidine ICI exerts a synergistic pro-erectile
effect in anesthetized rats: guanethidine ICI depletes tissue stores of NE and decreases …

… and sexual performance–enhancing drugs (eg, Viagra, Cialis, … Guanethidine and
clonidine oppose the action of the … and verapamil) and hydralazine have negative effects on …

… sildenafil, tadalafil, vardenafil and avanafil, are a group of dugs effective in the management
of erectile dysfunction … ), and the magnesium-ATPase inhibitor guanethidine are considered …