… Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney
damage by increasing uromodulin expression. Nat Med 2013;19:1655–60. https://doi.org/…

… dominant polycystic kidney disease but pathogenic gene variants especially associated …
Common UMOD variants have been associated with salt-sensitive hypertension, possibly by a …

… recognized association between chronic kidney disease (CKD) and … renal function, and
hypertension (89), and that non-coding UMOD gene variants induce salt-sensitive hypertension …

… Trudu M, Janas S, Lanzani C, et al ; Swiss Kidney Project on Genes in Hypertension (…
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage …

… the influence of the UMOD-PDILT locus on kidney function. … , 6 modulating salt reabsorption
and blood pressure control. … identified common variants within the promoter of UMOD as the …

… cause autosomal dominant tubulointerstitial kidney disease (ADTKD) [11], that specific …
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage …

… Umod expression in transgenic mice led to salt-sensitive hypertension (owing to Umod-…
In our eGFR GWAS, the observed UMOD effect on kidney function was greater in patients …

… Multiple loci associated with indices of renal function and chronic kidney disease. Nat …
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage …

… We had genetic information on the UMOD promoter variant rs12917707 in … salt-sensitive
component of BP regulation. Uromodulin levels may help in stratifying patients as “salt sensitive,…

… is influenced by common variants in the UMOD gene, and it … the uromodulin (UMOD)
gene coding for uromodulin cause a … of kidney damage and an NaCl-sensitive hypertension …