Comparison of canine and human physiological factors: understanding interspecies differences that impact drug pharmacokinetics
… To appreciate the canine-human differences that can … a comparison of the physiology, drug
transporter/enzyme location, abundance, activity, and specificity between dogs and humans. …
transporter/enzyme location, abundance, activity, and specificity between dogs and humans. …
Comparing dog and human intestinal fluids: implications on solubility and biopharmaceutical risk assessment
PL Walsh, J Stellabott, R Nofsinger, W Xu… - AAPS …, 2017 - Springer
… Despite many documented differences in gut physiology compared to humans, the beagle
dog … However, differences in pH and bile salt concentration and micellar structure between …
dog … However, differences in pH and bile salt concentration and micellar structure between …
The canine gastrointestinal microbiota: early studies and research frontiers
Z Huang, Z Pan, R Yang, Y Bi, X Xiong - Gut Microbes, 2020 - Taylor & Francis
… canine gut microbiota is similar to the human gut microbiota, and dietary factors affect both.
Studying canine intestinal … the canine GI microbiome revealed that differences in the levels of …
Studying canine intestinal … the canine GI microbiome revealed that differences in the levels of …
In vitro models of the canine digestive tract as an alternative to in vivo assays: Advances and current challenges
C Deschamps, S Denis, D Humbert… - ALTEX-Alternatives …, 2022 - refubium.fu-berlin.de
… digestion and gut microbiota as key factors in dog nutrition … similarities and differences
between the human and canine … key process in both dog and human gut physiology. To further …
between the human and canine … key process in both dog and human gut physiology. To further …
Variation of the microbiota and metabolome along the canine gastrointestinal tract
… gastrointestinal physiology, the goal of this study was to sample multiple sites along the
canine … ), treating each dog as a block and testing for significant differences with Kruskal–Wallis …
canine … ), treating each dog as a block and testing for significant differences with Kruskal–Wallis …
[HTML][HTML] A comparative assessment of the diagnosis of swallowing impairment and gastroesophageal reflux in canines and humans
TV Ullal, SL Marks, PC Belafsky, JL Conklin… - Frontiers in Veterinary …, 2022 - frontiersin.org
… Similarities in anatomy and physiology between humans and canines results in analogous
… Accordingly, the diagnostic approach to human and canine patients with swallowing …
… Accordingly, the diagnostic approach to human and canine patients with swallowing …
Canine and feline parasitology: Analogies, differences, and relevance for human health
S Morelli, A Diakou, A Di Cesare… - Clinical microbiology …, 2021 - Am Soc Microbiol
… based on different preys for dogs and cats, (ii) … similarities than differences in canine and
feline infections and associated diseases. Differences, similarities, and peculiarities of canine …
feline infections and associated diseases. Differences, similarities, and peculiarities of canine …
[HTML][HTML] The role of the canine gut microbiome and metabolome in health and gastrointestinal disease
R Pilla, JS Suchodolski - Frontiers in veterinary science, 2020 - frontiersin.org
… meat-based raw diets in the gut microbiome of healthy dogs in comparison with kibble-fed …
, can have an impact on the gut microbiome. In a study comparing dogs and their owners, …
, can have an impact on the gut microbiome. In a study comparing dogs and their owners, …
Comparison of healthy adult and puppy canine intestinal epithelium histological features
V Livania - 2022 - search.proquest.com
… pathophysiology of intestinal diseases that take place in humans. This … canines, because
canine gut physiology, diet, and intestinal microbiota are highly comparable to those of humans…
canine gut physiology, diet, and intestinal microbiota are highly comparable to those of humans…
Exploring Canine-Human Differences in Product Performance. Part II: Use of Modeling and Simulation to Explore the Impact of Formulation on Ciprofloxacin In Vivo …
MN Martinez, B Mistry, V Lukacova, KA Lentz, JE Polli… - The AAPS journal, 2017 - Springer
… Therefore, it is necessary to understand the interrelationship between drug physiochemical
characteristics, GI physiological attributes, and product formulation. Achieving this insight is …
characteristics, GI physiological attributes, and product formulation. Achieving this insight is …