Systemic lupus erythematosus as a genetic disease
ITW Harley, AH Sawalha - Clinical Immunology, 2022 - Elsevier
… how these disease-associated genetic variations mediate … With this in mind, it would seem
that if a particular disease associated … modifications and chromatin conformation, such that …
that if a particular disease associated … modifications and chromatin conformation, such that …
The Ankylosing Spondylitis-associated HLA-B* 2705 presents a B* 0702-restricted EBV epitope and sustains the clonal amplification of cytotoxic T cells in patients
V Tedeschi, C Vitulano, A Cauli, F Paladini, M Piga… - Molecular …, 2016 - Springer
… molecule, since it is not shared by the closely related, non-disease associated B*2709. …
Very recently, the characterization of Behçet’s disease-associated B*5101 peptidome revealed …
Very recently, the characterization of Behçet’s disease-associated B*5101 peptidome revealed …
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis
… Calculating the ‘credible set’ of markers for each locus through a Bayesian approach that
selected markers likely to contain the causal disease-associated markers (Supplementary …
selected markers likely to contain the causal disease-associated markers (Supplementary …
[图书][B] Lahita's Systemic Lupus Erythematosus
RG Lahita - 2021 - books.google.com
… Because its symptoms come and go and mimic those of other diseases, lupus is difficult to
diagnose. There is no single laboratory test that can definitively prove that a person has the …
diagnose. There is no single laboratory test that can definitively prove that a person has the …
Modeling autoimmune associated genetics in primary human T cells using CRISPR/Cas9 gene editing
WR Anderson - 2019 - digital.lib.washington.edu
… binding of self-peptides in a manner that promotes self-reactivity, molecular mimicry, and …
residues on these proteins, altering their conformation and ceasing their activity78,79. This co-…
residues on these proteins, altering their conformation and ceasing their activity78,79. This co-…
Zur Rolle von HLA-B27 in der Pathogenese und Diagnostik der axialen Spondyloarthritis
J Braun, M Rudwaleit, J Sieper - Zeitschrift für Rheumatologie, 2024 - Springer
… The physiological function of HLA class I molecules is the defence of the organism against
microbes. Microbial peptides are presented to the immune system, which can be specifically …
microbes. Microbial peptides are presented to the immune system, which can be specifically …