Partner-facilitating transmembrane penetration of nanoparticles: a biological test in silico

W Wang, R Yang, F Zhang, B Yuan, K Yang, YQ Ma - Nanoscale, 2018 - pubs.rsc.org
… An increase in the number of partner NPs would further promote the inter-NP cooperation
and make the transmembrane penetration of the host NP much easier. The WNP is taken as …

The cooperative effect analysis when nanoparticles enter a biological cell

F Liu, D Wu, K Chen - Nano, 2019 - World Scientific
… They also found that a partner NP would greatly facilitate the transmembrane penetration of
a … of NPs that are used in experiment where their cooperative e®ect should be concerned.…

Molecular understanding of the penetration of functionalized gold nanoparticles into asymmetric membranes

X Quan, C Peng, D Zhao, L Li, J Fan, J Zhou - Langmuir, 2017 - ACS Publications
In this work, the interactions between surface-functionalized gold nanoparticles (AuNPs)
and asymmetric membranes and the associated cytotoxicity were explored by coarse-grained …

Simulations of Cell Uptake of Nanoparticles: Membrane‐Mediated Interaction, Internalization Pathways, and Cooperative Effect

F Tian, T Yue, Y Li, X Zhang - Self‐Assembling Systems: Theory …, 2016 - Wiley Online Library
transmembrane penetration. Recently, Zhang et al. [14, 52] used DPD simulations to study
the transmembrane penetration … the NP penetration process. Additionally, some interesting …

Curvature-mediated cooperative wrapping of multiple nanoparticles at the same and opposite membrane sides

Z Yan, Z Wu, S Li, X Zhang, X Yi, T Yue - Nanoscale, 2019 - pubs.rsc.org
… are believed to be wrapped cooperatively by the membrane … we systematically investigate
the cooperative effect in the … sides is always attractive and the cooperative wrapping of NPs is …

Direct permeation of nanoparticles across cell membrane: a review

H Nakamura, S Watano - KONA Powder and Particle Journal, 2018 - jstage.jst.go.jp
… Current status of technologies for facilitating the direct permeation of nanoparticle is …
multiple NPs cooperatively interact with a membrane and form a transmembrane pore. This …

Interplay of nanoparticle rigidity and its translocation ability through cell membrane

L Zhang, H Chen, J Xie, M Becton… - The Journal of Physical …, 2019 - ACS Publications
… the mechanism of transmembrane penetration for multiple NPs … not deformable, the
transmembrane penetration process of two … understanding for the cooperative penetration of …

Ligand–receptor interaction-mediated transmembrane transport of dendrimer-like soft nanoparticles: Mechanisms and complicated diffusive dynamics

J Liang, P Chen, B Dong, Z Huang, K Zhao… - …, 2016 - ACS Publications
nanoparticles, that is, the direct wrapping and the penetration… architecture of such soft
nanoparticles. The results gain insight … and thereby influence the cooperative effect in endocytosis. …

Counterintuitive cooperative endocytosis of like-charged nanoparticles in cellular internalization: computer simulation and experiment

Y Li, B Yuan, K Yang, X Zhang, B Yan, D Cao - Nanotechnology, 2017 - iopscience.iop.org
… charged nanoparticles plays an important role in the 'bud' cooperative … normal cooperative
endocytosis, we also found a new cooperative endocytosis pathway that is 'bud' cooperative

Strategies to overcome/penetrate the BBB for systemic nanoparticle delivery to the brain/brain tumor

HJ Liu, P Xu - Advanced drug delivery reviews, 2022 - Elsevier
… tight junctions (TJs) through a number of transmembrane proteins (such as occludin, claudins,
… and the penetrating efficiency of BBTB for macromolecule and nanoparticles are highly …