… Pain Assessment in Clinical Trials (IMMPACT) has recommended 6 core outcome domains
that should be considered when designing clinical trials: (1) pain, (2) physical functioning, (3) …

… In a previous article, IMMPACT recommended that to assess health-related quality of life (…
be included as core outcome domains in all chronic pain clinical trials. Investigators should …

… the clinical domains that should be evaluated in clinical trials evaluating treatments for chronic
pain, researchers may use the domains … Second, we chose to focus on public clinical trial …

… Chronic pain clinical trials have historically assessed benefit and risk outcomes separately.
… composite measures across chronic pain clinical trials has not been adequately evaluated. …

… , responses to noxious stimulation, endogenous pain-modulatory processes, and response
… recommendations for core phenotyping domains and recommend measures of each domain…

… clinical interventions for pediatric chronic pain. Building on the work of the Ped-IMMPACT
group, we previously updated a core outcome set (COS) for pediatric chronic pain clinical trials …

… with chronic pain. Our aim was to update a core outcome set for pediatric chronic pain …
treatment of pediatric chronic pain to understand clinically meaningful outcomes to be routinely …

… for pain to choose from. To ensure consistency and uniformity in clinical trials and systematic
reviews, core outcome … all 6 IMMPACT domains recommended for chronic pain, while five …

… for chronic pain. One of the 23 SR authors stated that they would endorse the IMMPACT-recommended
core outcome domains, while others proposed one to four outcome domains of …

… the authors specified 3 IMMPACT chronic pain core outcome domains (pain, physical function…
The core outcomes reporting in clinical trials is considered a minimum requirement, 2 not a …