… the presence of BRAF V600E mutation correlated with worse … with germline mutations present
with left-sided colon cancer at a … impact of BRAF V600E mutation and MLH1/PMS2 loss on …

… /or MLH1 hypermethylation and no MMR germline mutation. … considering collinearity among
variables with a correlation matrix. … of BRAF mutation and MLH1 methylation, nine Lynch-like …

… that tumor initiation may precede the loss of mismatch repair … in the germline, retained mismatch
repair protein expression in … “C” of MLH1 (MLH1-I probe); hypermethylation of this region …

… In this review we will describe the relationship between MMR … hypermethylation of MLH1
rather than germline mutations in … , IHC for MMR proteins, and BRAF mutation screening (as …

… tumors without BRAF mutation should be followed up by germline MLH1 testing, regardless
of the MLH1 methylation … occurrence – correlation between the germline mutation status and …

… V600E mutations (9 had somatic mutations of MMR genes) in … BRAF mutations are correlated
with MLH1 methylation,40, … MSI tumors could develop through MLH1 promoter methylation …

… of germline pathogenic variants in other non-MMR cancer … Given that MSI and IHC are
highly correlated, we generated … integrating BRAF mutation or MLH1 methylation status in our …

… germline mutations versus sporadic mutations, which include but not limited to those with
BRAF V600E mutation with MLH1 promoter hypermethylation. … MMR-D tumors, BRAF mutations …

… expression and no mismatch repair germline mutations were … mutations of MMR genes,
somatic mutations of driver genes, … , tumor neoantigen burden has recently been correlated with …

… by germline mutations in mismatch repair (MMR) genes (MLH1… for both MLH1 methylation
and BRAF mutation we had germline … Lynch Syndrome with a germline PV in MLH1 gene. One …