Objectives: Cost-effectiveness analyses are increasingly used to aid decisions about
resource allocation in healthcare; this practice is slow to translate into critical care. We
sought to identify and summarize original cost-effectiveness studies presenting cost per
quality-adjusted life year, incremental cost-effectiveness ratios, or cost per life-year ratios for
treatments used in ICUs. Design: We conducted a systematic search of the English-
language literature for cost-effectiveness analyses published from 1993 to 2018 in critical …