Inhibition of autophagy promotes apoptosis and enhances anticancer efficacy of adriamycin via augmented ROS generation in prostate cancer cells
J Wang, X Tan, Q Yang, X Zeng, Y Zhou, W Luo… - … International Journal of …, 2016 - Elsevier
… role of autophagy in adriamycin-induced apoptosis, as well as … Scavenging of ROS by
antioxidant N-acetyl-cysteine (NAC) … The results showed that little effect of ADM administration was …
antioxidant N-acetyl-cysteine (NAC) … The results showed that little effect of ADM administration was …
Time course of changes in oxidative stress and stress-induced proteins in cardiomyocytes exposed to doxorubicin and prevention by vitamin C
A Ludke, G Akolkar, P Ayyappan, AK Sharma… - PLoS …, 2017 - journals.plos.org
… Dox administration to cardiomyocytes increased the levels of ROS in a time-dependent …
under Dox exposure; Vit C could effectively counteract all Dox-induced changes in …
under Dox exposure; Vit C could effectively counteract all Dox-induced changes in …
Phosphocreatine attenuates doxorubicin-induced cardiotoxicity by inhibiting oxidative stress and activating TAK1 to promote myocardial survival in vivo and in vitro
C Wang, L Hu, S Guo, Q Yao, X Liu, B Zhang, X Meng… - Toxicology, 2021 - Elsevier
… or without PCr (0.5 mM) or N-Acetyl-L-cysteine (NAC, 0.5 mM) or … antioxidant activity counteract
to oxidative stress through … administration of exogenous PCr alleviated oxidative stress, …
to oxidative stress through … administration of exogenous PCr alleviated oxidative stress, …
[PDF][PDF] The Antitumor effect of Tetrodotoxin or/and Doxorubicin with or without N-Acetylcysteine on Some Biochemical Alterations in Ehrlich Carcinoma-Bearing Female …
SM Abd El Dayem, FM Fouda, EHA Ali… - researchgate.net
… a result of liver oxidative damage and reduction of liver metabolism that led to the presence
of oxygen and production of reactive oxygen species induced by DOX administration (Swift …
of oxygen and production of reactive oxygen species induced by DOX administration (Swift …
Omega-3 fatty acids ameliorate doxorubicin-induced cardiorenal toxicity: In-vivo regulation of oxidative stress, apoptosis and renal Nox4, and in-vitro preservation of …
D Saleh, M Abdelbaset, A Hassan, O Sharaf… - Plos one, 2020 - journals.plos.org
… The data suggests OMG for protection against acute DOX‐induced cardiorenal damage
without affecting the latter antitumor activity. It proposes regulation of oxidative stress, Nox4 …
without affecting the latter antitumor activity. It proposes regulation of oxidative stress, Nox4 …
[HTML][HTML] Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation
Q Wu, W Li, J Zhao, W Sun, Q Yang, C Chen… - Biomedicine & …, 2021 - Elsevier
… antibiotic widely utilized in treating various tumors. Nevertheless, … The APG-treated groups
were administered various … (B) Effects of APG and N-acetyl-l-cysteine (NAC) on DOX-elicited …
were administered various … (B) Effects of APG and N-acetyl-l-cysteine (NAC) on DOX-elicited …
[HTML][HTML] Reduced chemotherapeutic sensitivity in high glucose condition: Implication of antioxidant response
… ) and consequently on the oxidative stress that exceeds the … damage and cell death,
attenuated by HG. We found that the lack of H2AX phosphorylation in ADR/HG was counteracted by …
attenuated by HG. We found that the lack of H2AX phosphorylation in ADR/HG was counteracted by …
[HTML][HTML] Melatonin ameliorates the drug induced nephrotoxicity: Molecular insights
Z Raza, Z Naureen - nefrologia, 2020 - Elsevier
… -dependant manner which follows the formation of AFMK (N-acetyl-N-formyl-5-methoxykynuramine) …
co-administration was found to attenuate the adriamycin-induced oxidative stress by …
co-administration was found to attenuate the adriamycin-induced oxidative stress by …
Rutin inhibits carfilzomib-induced oxidative stress and inflammation via the NOS-mediated NF-κB signaling pathway
NO Al-Harbi, F Imam, MM Al-Harbi… - …, 2019 - Springer
… and biochemical analyses, determined oxidative stress, caspase-3 … nephrotoxicity and its
prevention by rutin administration. … A case report suggested N-acetyl cysteine may exert renal …
prevention by rutin administration. … A case report suggested N-acetyl cysteine may exert renal …
Nanoceria ameliorates doxorubicin induced cardiotoxicity: Possible mitigation via reduction of oxidative stress and inflammation
… of DOX administration in mice. We believe that amelioration of … a well-known antioxidant,
N-acetyl cysteine [41]. Although the … Adriamycin-induced oxidative mitochondrial cardiotoxicity …
N-acetyl cysteine [41]. Although the … Adriamycin-induced oxidative mitochondrial cardiotoxicity …