[HTML][HTML] Targeted delivery of immunostimulatory CpG oligodeoxynucleotides to antigen-presenting cells in draining lymph nodes by stearic acid modification and …
M Nagaoka, W Liao, K Kusamori… - International journal of …, 2022 - mdpi.com
… the application of CpG ODNs as immunostimulatory adjuvants… and DNA hydrogel consisting
of SA-conjugated CpG ODN. … for the Care and Use of Laboratory Animals. The protocols for …
of SA-conjugated CpG ODN. … for the Care and Use of Laboratory Animals. The protocols for …
A visible codelivery nanovaccine of antigen and adjuvant with self-carrier for cancer immunotherapy
X Dong, J Liang, A Yang, Z Qian… - ACS applied materials …, 2019 - ACS Publications
… After the tumor model was established, the animals were grouped and administered with …
First of all, only a small proportion of free CpG oligodeoxynucleotide could enter into the DCs. …
First of all, only a small proportion of free CpG oligodeoxynucleotide could enter into the DCs. …
[HTML][HTML] Nucleic acids presenting polymer nanomaterials as vaccine adjuvants
A Comberlato, K Paloja, MMC Bastings - Journal of materials …, 2019 - pubs.rsc.org
… -motif-containing oligodeoxynucleotides (ODNs), which are … that have been most extensively
characterized in animals … and TLR adjuvants in the context of cancer immunotherapy has …
characterized in animals … and TLR adjuvants in the context of cancer immunotherapy has …
[HTML][HTML] Nanovaccines for cancer prevention and immunotherapy: an update review
X Fang, H Lan, K Jin, D Gong, J Qian - Cancers, 2022 - mdpi.com
… of antigenic peptide, CpG oligodeoxynucleotides and cationic … ) to carry the unmethylated
CpG adjuvant and OVA antigen … of the B16F10 model animals. Furthermore, approximately half …
CpG adjuvant and OVA antigen … of the B16F10 model animals. Furthermore, approximately half …
Tailoring inorganic nanoadjuvants towards next-generation vaccines
… pot method as novel adjuvants for cancer immunotherapy. Cu- and … CpG oligonucleotides,
shows potential in cancer … (PEI) were used as adjuvant in DNA vaccines for HIV treatment. For …
shows potential in cancer … (PEI) were used as adjuvant in DNA vaccines for HIV treatment. For …
Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity
… performed on bacterial DNA and its synthetic mimic, CpG oligodeoxynucleotides (CpG ODN)
[52]. … motifs occur at higher frequency in bacterial and viral DNA than vertebrate DNA [54]. …
[52]. … motifs occur at higher frequency in bacterial and viral DNA than vertebrate DNA [54]. …
Targeting CpG adjuvant to lymph node via dextran conjugate enhances antitumor immunotherapy
… (39, 40) We believe that this “sticky” feature of CpG DNA … types of TLR agonists, including
RNA oligonucleotides and non-… , we used group sizes of 4 animals/group for immunogenicity …
RNA oligonucleotides and non-… , we used group sizes of 4 animals/group for immunogenicity …
Molecular mechanisms for enhanced DNA vaccine immunogenicity
L Li, N Petrovsky - Expert review of vaccines, 2016 - Taylor & Francis
… formulation of DNA vaccines with traditional or molecular adjuvants. … laboratory animals are
principally used for DNA vaccine … [Citation65] A combined CpG/Poly (I:C) adjuvant enhanced …
principally used for DNA vaccine … [Citation65] A combined CpG/Poly (I:C) adjuvant enhanced …
Structure, mechanism and therapeutic utility of immunosuppressive oligonucleotides
… The release of inhibitory DNA as host cells die may serve to down-regulate pathologic … in
complete Freund’s adjuvant into the hind footpads of Lewis rats. When animals with EIN were …
complete Freund’s adjuvant into the hind footpads of Lewis rats. When animals with EIN were …
… of orthotopic genital cancer induced by subcutaneous administration of human papillomavirus peptide vaccine with CpG oligodeoxynucleotides as an adjuvant in …
H Wang, Y Che, Y Yang, J Suo… - Cancer Management and …, 2021 - Taylor & Francis
Purpose Persistent high-risk human papillomavirus (HPV) infection is the most common
cause of cervical cancer and its precursor lesions. Although prophylactic HPV vaccines have …
cause of cervical cancer and its precursor lesions. Although prophylactic HPV vaccines have …