[HTML][HTML] Melanin-loaded CpG DNA hydrogel for modulation of tumor immune microenvironment

Y Wu, Q Li, G Shim, YK Oh - Journal of controlled release, 2021 - Elsevier
… for photothermal immunotherapy. To this end, we designed a … For dual adjuvant effects, we
used CpG-amplified DNA hydrogel … Immunotherapeutic uses of CpG oligodeoxynucleotides

Designer vaccine nanodiscs for personalized cancer immunotherapy

R Kuai, LJ Ochyl, KS Bahjat, A Schwendeman… - Nature materials, 2017 - nature.com
… identified via tumour DNA sequencing, to … animals with the equivalent doses of Ag and CpG
emulsified in water-in-oil Montanide, which is arguably one of the strongest adjuvant systems …

Comparative study of adjuvants for allergen-specific immunotherapy in a murine model

MV de la Torre, ML Baeza, L Nájera, JM Zubeldia - Immunotherapy, 2018 - Future Medicine
… (ISS) of DNA, also known as CpG-oligodeoxynucleotides [9], are … synthetic phosphorothioated
oligonucleotides of DNA with the 5… Later, the animals were vaccinated with the olea extract …

A visible codelivery nanovaccine of antigen and adjuvant with self-carrier for cancer immunotherapy

X Dong, J Liang, A Yang, Z Qian… - ACS applied materials …, 2019 - ACS Publications
… After the tumor model was established, the animals were grouped and administered with …
First of all, only a small proportion of free CpG oligodeoxynucleotide could enter into the DCs. …

[HTML][HTML] Exploiting bacterial-origin immunostimulants for improved vaccination and immunotherapy: current insights and future directions

G Wang, Y Wang, F Ma - Cell & Bioscience, 2024 - Springer
CpG motifs are unique to microbial DNA since vertebrateDNA can be mimicked by synthetic
oligodeoxynucleotides … Halperin et al. first reported CpG used as the sole adjuvant and the …

Nanoparticle-based immunotherapy: state of the art and future perspectives

M Di Gioacchino, C Petrarca, A Gatta… - Expert Review of …, 2020 - Taylor & Francis
… Aptamers (oligonucleotides or peptides that bind to a specific … CpG-DNA and allergens and
act as both adjuvant and … NPs significantly protected challenged animals from anaphylaxis, …

[HTML][HTML] Toll-like receptor agonists as adjuvants for allergen immunotherapy

ME Kirtland, DC Tsitoura, SR Durham… - Frontiers in …, 2020 - frontiersin.org
… evolutionarily conserved between invertebrates and vertebrates. The functional importance
of … in contrast to mammalian DNA (149). A range of CpG-Oligodeoxynucleotides (CpG-ODNs) …

Advances in immunotherapy delivery from implantable and injectable biomaterials

DG Leach, S Young, JD Hartgerink - Acta biomaterialia, 2019 - Elsevier
… with various adjuvants and immunotherapies could rescue the … in vertebrate DNA, are
common in bacteria such that the immune system has adapted to recognize CpG oligonucleotides

DNA and mRNA vaccination against allergies

S Scheiblhofer, J Thalhamer… - Pediatric Allergy and …, 2018 - Wiley Online Library
… ), the use of adjuvants such as CpG oligodeoxynucleotides (… -rich DNA sequences (CpG-motifs)
either as adjuvant or even … in allergen-specific immunotherapy. These sequences are …

Immunotherapeutic nanoparticles: From autoimmune disease control to the development of vaccines

R Mitarotonda, E Giorgi, T Eufrasio-da-Silva… - Biomaterials …, 2022 - Elsevier
… In addition, immunotherapeutic NPs for cancer and adjuvant NPs to improve vaccines are …
contrary, DNA microcapsules made of cytosine–phosphate–guanosine oligodeoxynucleotides