… Here we present crystal structure of the O-intermediate of the physiologically … light-driven
Na + pump KR2 was identified in Krokinobacter eikastus in 2013 2 . Its functional and structural …

… of the crystal structures, potassium-translocating variants were designed [12, 13], representing
the first examples of outwardly directed light-driven potassium pumps. Such pumps are …

… Light-driven sodium pumps actively transport small cations across cellular membranes 1 .
These pumps … The serial crystallographic structure of the KR2 resting state closely resembles …

… structure-function relationships in these three light-driven pumps, mainly focusing on Na +
pumps. … Gushchin et al. solved crystal structures of KR2 32, 33, and now we can compare the …

… However, no structural data on the functional conversions of the light-driven sodium pumps
are available at the moment. Here we present the crystal structure of the N112A mutant of …

… To better understand the molecular mechanism, structural information is very important,
and next X-ray crystallographic structures of a light-driven sodium pump will be introduced. …

… Crystal structures of KR2 at acidic and neutral pHs displayed a change in the orientation of
D116, suggesting that D116 interacts with the Schiff base in the dark, while protonated D116 …

… (7) also found that these residues form contacts with Asp116 in crystal structures obtained
under acidic conditions. The flipping of Asp116 occurs concertedly with the closing motion of …

… Na + pumping is unknown, in part because KR2 adopts both pentamer and monomer forms
in crystal structures and in part because these structures … for each crystal structure, using a …

… However, the crystal structure of mutant G263F, which can pump K + , has demonstrated a
dramatically reduced ion uptake cavity rather than an enlarged one as would be expected to …