… that activates TLR2 in a strictly MyD88-dependent manner, P. gingivalis strikingly induced
TLR2 … or antibody-mediated inactivation of TLR2 completely reduced cytokine production in P. …

… gingivalis, 293-TLR2 cells alone were activated in a density-dependent manner (Figure 4A).
These findings suggest that the observed cytokine production by BEAS-2B and Detroit 562 …

… In humans, the black-pigmented bacterium Porphyromonas gingivalis has been shown to
be associated with … gingivalis, the similarities to the immune response shown by our data for …

… gingivalis benefits from TLR2-driven signaling via activation of PI3K. … TLR2 protein-protein
interactions induced in response to P. gingivalis, and identified an interaction between TLR2 …

… Among the top protein clusters induced to interact with TLR2 following macrophage
activation, we observed mono-ADP-ribosyltransferase protein 9 (PARP9) and its known complex …

… TLR2 responds to … activation of TLR2/1 or TLR2/6 complexes [76]. Moreover, TLRs engage
in signaling crosstalk with the complement system, apparently to coordinate innate immunity …

… several gram-negative bacteria, including Porphyromonas gingivalis, initiates the cascade
of a … receptor activation, we knocked down TLR2 by using small interfering RNA designed to …

… Cutting edge: TLR2 is required for the innate response to Porphyromonas gingivalis:
activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone …

… bacteria, including Porphyromonas gingivalis (Pg), and it acts … the inflammatory adaptive
immune response, mimicking an … , we demonstrate that TLR2 and not TLR4 activation plays an …

… Cutting Edge: TLR2 is required for the innate response to Porphyromonas gingivalis:
activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone …