… a novel role for BCL‑3 in colorectal cancer and suggested that expression of BCL‑3 may be
a key determinant in the COX‑2‑meditated response to inflammatory cytokines in colorectal …

… as a potent therapeutic strategy for treatment of colon cancer. In this review, we try to
clarify the role of PGE2 in cancer progression and its targeting for treatment of colon cancer. …

… COX-2 (cyclooxygenase 2) is involved in drug resistance … mechanism underlying colorectal
cancer development and … is still crucial for successful colorectal cancer treatment [17]. …

… in HT-29 colorectal cancer cells. 17-AAG inhibited PMA-induced cyclooxygenase-2 (COX-2) …
on PGE2 levels in HT-29 colorectal cancer cells were mediated through modulating COX-2 …

… was detected in colorectal cancers when compared to the … almost 11% of colorectal carcinoma.
Egypt Demographic Survey (… with their effect on overall survival in Colorectal Carcinoma (…

… However, rs5279 T>C in the exon region and rs4648298A>G in the 3′ UTR may reduce
the risk of gastric and colorectal cancers (TC vs TT: OR = 0.24, 95%CI: 0.08-0.73 and G vs A: …

… Several studies have shown that long-term administration of non-steroidal anti-inflammatory
drugs protects against colon cancer and potentially other tumor types by interfering both …

… One of the most serious complications of IBD is colorectal cancer (CRC). Patients with IBD
are at a higher risk of developing CRC compared to the general population [1]. The incidence …

… intrinsic driver of immunosuppression, through TGF-β pathway in pancreatic cancer (18).
The reduction of RIPK3 in colorectal cancer cells and MDSCs elicited NF-κβ-transcribed COX-2…

… Prostaglandin-endoperoxide synthase 2 (PTGS2, cyclooxygenase-2, COX-2) regulates the
… chronic inflammation and plays important roles in the development of colorectal cancer [1], [2]…