… cells is 100-fold higher in colon cancer compared to normal colonic epithelium (11). … colorectal
carcinoma cells (24, 25). In mice, EP2 receptors are involved in skin tumour development (…

… Cyclooxygenase-2, which plays a key role in the biosynthesis of prostaglandin E 2 (PGE 2 ),
… the proliferation of colon and breast cancer cells [22–24]. Here, we investigated their roles in …

… polyps in patients whereas Etoricoxib, a second generation selective cyclooxygenase-2 (COX-2)
inhibitor having chloromethyl sulfonyl bipyridine group and found to be highly effective …

… Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential.
Proceedings of the National Academy of Sciences of the United States of America, 94, 3336–…

… of developing cancer, distinctive response to treatment, and prognosis. Cyclooxygenase-2
(… in inflammatory diseases, precancerous lesions and colorectal cancer (CRC). The aim of this …

… was associated with colorectal cancer risk. Another study by Wang et al Citation38 found
that COX-2 overexpression was associated with poor prognosis and cancer progression. COX-…

… of Cox2 and CDX2 in colorectal carcinoma and correlate their expression with the available
… on the role of Cyclooxygenase 2 (Cox2) in tumor development and progression [14] . …

… Conclusions: Our data support that COX-2 is involved in the early stages of colorectal cancer
development, initially affecting the tumor’s stromal microenvironment, and, subsequently, …

… colon cancer azoxymethane/dextran sulfate sodium (AOM/DSS-treated mice), and in human
colorectal tumors … , we demonstrate that treatment with cyclooxygenase 2 (COX2) inhibitors …

… To explore the possible role of SFN in tumor progression, we evaluated its potential to
modify the motility/wound-healing activity of HT-29 cells. In the scratch test, we observed a …