… identification of a specific therapeutic target for the management of sepsis in the clinics and
… The decreased expression of HLA-DR and cytokine production was observed even at 28 th …

… sepsis to design future target-based therapeutics depending on the severity. The current …
Both these factors, infection and inflammatory cytokines, are present in systemic circulation …

Sepsis is a leading cause of death in intensive care units and survivors develop prolonged
immunosuppression and a high incidence of recurrent infections. No definitive therapy exists …

… potential applications of MDSCs as biomarkers and targets for clinical treatment of sepsis. …
For concomitant immunosuppression, the causative view is lymphocyte exhaustion and …

… -36α protected them against sepsis by boosting macrophage function [… biomarker and potential
therapeutic target in sepsis. … the immunoregulatory effects of IL-37 in the setting of sepsis. …

… cytokine networks in the immune response in both septic tissue and serum or plasma, since
… Future Perspective on HSP Modulators in Sepsis Treatment As a therapeutic targets, HSPs …

… In view of this, a recent study has devoted to provide accurate global sepsis estimates by
analyzing both in and out-hospital sepsis… cytokines also showed diverse immunoregulatory role …

… focuses upon release, impact, and potential therapy of a limited number of potent anti-inflammatory
cytokines. … This view is supported by studies examining specific organ failures in …

… Thus, the 'cytokine storm of sepsis' may direct the loss of … to identify more efficient therapeutic
targets that will lead to … blockade improves T cell functions after sepsis (see below). T cell …

… aimed to show the new therapeutic targets in sepsis treatment with current studies. New
clinical … inflammatory response in sepsis can contribute to the understanding of the symptoms. …