Cytomegalovirus in hematopoietic stem cell transplant recipients: prevention, diagnosis, and treatment
JF Camargo - Emerging transplant infections: clinical challenges and …, 2021 - Springer
Emerging transplant infections: clinical challenges and implications, 2021•Springer
Human herpesvirus 5, better known as cytomegalovirus (CMV), infects 50–90% of the adult
population worldwide and is the most common opportunistic infection in allogeneic
hematopoietic stem cell transplant (HSCT) recipients, causing significant morbidity and
mortality [,,,,–]. Without prophylaxis, CMV reactivation occurs in up to 70–80% of CMV-
seropositive individuals [,,–]. This chapter will review the current understanding of CMV
infection in HSCT recipients focusing on emerging concepts and updated recommendations …
population worldwide and is the most common opportunistic infection in allogeneic
hematopoietic stem cell transplant (HSCT) recipients, causing significant morbidity and
mortality [,,,,–]. Without prophylaxis, CMV reactivation occurs in up to 70–80% of CMV-
seropositive individuals [,,–]. This chapter will review the current understanding of CMV
infection in HSCT recipients focusing on emerging concepts and updated recommendations …
Abstract
Human herpesvirus 5, better known as cytomegalovirus (CMV), infects 50–90% of the adult population worldwide and is the most common opportunistic infection in allogeneic hematopoietic stem cell transplant (HSCT) recipients, causing significant morbidity and mortality [, , , , –]. Without prophylaxis, CMV reactivation occurs in up to 70–80% of CMV-seropositive individuals [, , –]. This chapter will review the current understanding of CMV infection in HSCT recipients focusing on emerging concepts and updated recommendations for CMV prevention, diagnosis, and management.
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