… expanding preferentially over subdominant ones (6, 7). IFNγ … and pulsed with corresponding
peptides (including one … The patients/participants provided their written informed consent to …

… The presence of cross-reactive cytotoxic T cells has even … , no T cell clone was available for
the two other WT epitopes. … responses to otherwise subdominant epitopes by modification of …

… (SLPs) containing immunodominant T cell epitopes. Previously, … Overall, this study provided
evidence that SLP-based … synthetic peptide vaccine-based immunotherapy against cancer. …

… Prediction and prioritization of conserved CD8 T cell epitopes derived from Porcine … targeted
cytotoxic T-cell response is given. These include the structure, polymorphisms and peptide …

… consist of epitopes capable to induce cytotoxic T cell responses (… directed to subdominant
conserved HIV-1 epitopes restricted to … The novel approach of synthetic peptides offers several …

… against subdominant E7 epitopes … I epitope of the HPV E7 antigen, provided significant
benefit when dosed therapeutically in the TC-1 tumor model. A major concern of using peptide …

… the memory T-cell response is broadly targeted against viral peptides … , epitope-specific CD8
+ T cells, synthetic peptides were … The data presented in this study are available on request …

… Cytotoxic T lymphocytes raised against a subdominant epitope offered as a synthetic
peptide eradicate human papillomavirus type 16-induced tumors. Eur J Immunol. (1995) 25:2638–…

… , binding motif, peptide origin and the T cell type they can … three is provided by DC-derived
cytokines and induces T cell … focus on immunodominant epitopes since also subdominant …

… of using synthetic peptides, containing both epitope sequences, to … of T cells reactive against
the immunodominant T cell epitopes, subdominant epitopes against which only few T cells …