[HTML][HTML] Catechin and epicatechin reduce mitochondrial dysfunction and oxidative stress induced by amiodarone in human lung fibroblasts

LFS Santos, A Stolfo, C Calloni, M Salvador - Journal of arrhythmia, 2017 - Elsevier
… (AMD) and its metabolite N-desethylamiodarone can cause some … the cytotoxicity induced
by AMD in MRC-5 cells. Although extrapolation of the results of cell culture studies to human

[HTML][HTML] Adverse reactions of Amiodarone

RMLC Biancatelli, V Congedo, L Calvosa… - Journal of geriatric …, 2019 - ncbi.nlm.nih.gov
… to find an association between Amiodarone and bilateral toxic vision … cells of peripheral
nerves in Amiodarone-associated … that the cytotoxicity induced by Amiodarone would decrease …

[HTML][HTML] Life cell imaging of amiodarone sequestration into lamellar bodies of alveolar type II cells

T Haller, A Jesacher, A Hidalgo, C Schmidt - Toxicology in Vitro, 2024 - Elsevier
… of amiodarone, we propose that passive diffusion, ion-trapping and lipophilic interactions are
… Furthermore, we demonstrate that measurement of amiodarone autofluorescence is highly …

[HTML][HTML] Amiodarone induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts

J Weng, M Tu, P Wang, X Zhou, C Wang, X Wan… - Biomedicine & …, 2019 - Elsevier
… studies have reported that amiodarone can cause lung epithelial cell injury by activating
necrotic cell death pathway or apoptotic pathways [18], the effect of amiodarone on fibroblasts is …

Insulin‐like growth factor‐1 activates PI3K/Akt signalling to protect human retinal pigment epithelial cells from amiodarone‐induced oxidative injury

R Liao, F Yan, Z Zeng, H Wang, K Qiu… - British Journal of …, 2018 - Wiley Online Library
… IGF-1 failed to suppress amiodarone-induced cytotoxicity and the … The amiodarone metabolite,
N-desethylamiodarone (DEA), … in amiodarone-induced toxicity in human peripheral lung

The role of amiodarone in contemporary management of complex cardiac arrhythmias

N Mujović, D Dobrev, M Marinković, V Russo… - Pharmacological …, 2020 - Elsevier
… There are no data on interactions between amiodarone and apixaban [54]. Therefore, a …
interactions with amiodarone. In selected patients at high risk of bleeding who take amiodarone, …

Pulmonary responses following quercetin administration in rats after intratracheal instillation of amiodarone

VO Oka, UE Okon, EE Osim - Nigerian Journal of Physiological Sciences, 2019 - ajol.info
… and vacuolization of the bronchial epithelial cell. This is … in normal peripheral blood
mononuclear cells via modulation of the NF-… Vitexin on activated human peripheral blood …

Amiodarone and thyroid physiology, pathophysiology, diagnosis and management

RG Trohman, PS Sharma, EA McAninch… - Trends in cardiovascular …, 2019 - Elsevier
Amiodarone's active metabolite N-desethylamiodarone (DEA),) has … Amiodarone has direct,
dose-dependent cytotoxic effects on the … These findings have been confirmed in human post-…

[HTML][HTML] Coadministration of atorvastatin and amiodarone increases the risk of pulmonary fibrosis in rats

HR Nasri, S Joukar, H Kheradmand… - Medical Principles and …, 2016 - karger.com
desethylamiodarone activates both necrotic and apoptotic pathways in the culture of human
peripheral lung epithelial cells … and the release of cytotoxic and inflammatory mediators such …

[PDF][PDF] Effects of 21-aminosteroid U-74389G on amiodarone-induced pulmonary toxicity in rats

GT STAVREVA, VY DANCHEVA, LG TERZIEV… - Arch Balk Med …, 2019 - umbalk.org
… olite N-desethylamiodarone can accumulate in the lungs in … mitochondrial dysfunction in
peripheral lung epithelial cells in early … cytotoxic effect on the alveolar-capillary membrane in the …