… [29] reported a single-cell cytotoxicity evaluation and selective release method. Natural …
quantified the drug amiodarone (AMIO) and its major metabolite, N-desethylamiodarone (NDEA), …

… located frequently in the liver and lungs, but also in the kidneys… : MTT cell viability assay for
cytotoxicity assessment and the … of amiodarone and the active metabolite desethylamiodarone…

… macrophages of the liver, spleen, and lung, among other locations. The accumulation of CFZ
… The inhibition resulting from the accumulation leads to significant cytotoxicity towards the …

… amiodarone formulations and included plasma levels of amiodarone and the active metabolite
desethylamiodarone… cell viability assay for cytotoxicity assessment and the chorioallantoic …

… lysosomal oxidation of SMase-LDL in human macrophages … import is initiated by the interaction
of the apolipoprotein B-100 (… injury or dysfunction as it is cytotoxic for endothelial cells in …

… , which appears to be related to a cytotoxic effect [18, 19]. Thyroid … Other actions of amiodarone
include blocking peripheral … Since amiodarone and its metabolite desethylamiodarone …

… in biomedical and therapeutic applications despite their cytotoxicity is yet unknown. [ Citation
131 ] … drug amiodarone and its primary metabolite, desethylamiodarone, within single lung …

Scientists from Canadian institutions have a rich history of making interesting and important
contributions to the journal Drug Metabolism and Disposition (DMD) over the past 51 years. …

… On the immune side, cytotoxic T cells and natural killer cells are the main effectors of the …
between activating and inhibiting signals coming from tumor targeted cells determines cytotoxic …

Thyroid disorders are among the most prevalent of medical conditions. Their manifestations
vary considerably from area to area and are determined principally by the availability of …