[图书][B] Functional Characterization of Identified DEAF1 Variants and Significance of HDAC1 Interactions on DEAF1-Mediated Transcriptional Repression

S Adhikari - 2021 - search.proquest.com
DEAF1 is a transcription factor that binds to TTCG motifs in … Methylated CpG dinucleotides
located in the promoter are … CpG methylation at the second half DEAF1 binding site on its …

Deaf1 and MeCP2 interact to coordinately regulate 5-HT1A receptor gene expression

T Philippe - 2016 - ruor.uottawa.ca
Deaf1 is unable to bind and regulate its site at the the G(1019) allelic variant. Note that the
C(-1019)G polymorphism is a CpG methylation … DNA methylation affect Deaf1 or MeCP2 bind- …

Expansion and mechanistic insights into de novo DEAF1 variants in DEAF1-associated neurodevelopmental disorders

SR McGee, S Rajamanickam, S Adhikari… - Human molecular …, 2023 - academic.oup.com
… a known DEAF1 binding region within the Deaf1 promoter or … a potential zinc binding motif
within the DNA binding domain. … ) bp between the required CG dinucleotides in the half-sites (…

ChIP-seq analysis of AIRE, FEZF2 and DEAF1 transcription factors in human thymus tissue

DR Aronsen - 2020 - nmbu.brage.unit.no
… it to determine the genomic binding sites of FEZF2, AIRE and DEAF1 in the infant human …
variable region that make up the antigen-binding region of the IG. The variable region binds

DNA methylation mediates BmDeaf1-regulated tissue- and stage-specific expression of BmCHSA-2b in the silkworm, Bombyx mori

G Xu, J Zhang, H Lyu, Q Song, Q Feng, H Xiang… - Epigenetics & …, 2018 - Springer
… Five CREs were predicted and Deaf1 CRE in the 5th CpG … is coincidence with their
expression patterns: BmCHSA-2a is … -2b transcription by binding to the unmethylated CpGI2 of …

[PDF][PDF] Ra amanickam

SR McGee - S., dhikari, S., Fala i, OC, Wilson, T …, 2022 - scholarlypublications …
… designed to amplify a known DEAF1 binding region within the Deaf1 promoter or the Ube2m
… (2014) DEAF1 binds unmethylated and variably spaced CpG dinucleotide motifs. PLoS One…

Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes

TJ Philippe, F Vahid-Ansari, ZR Donaldson… - Scientific Reports, 2018 - nature.com
binding protein MeCP2 may alter Deaf1 regulation at the HTR1A locus. We show that MeCP2
enhances Deaf1 binding … indirectly via binding to Deaf1 and directly via CpG methylation of …

Histone lysine methylation, demethylation, and hormonal gene regulation

Y Huang, B Dennehey, X Shi - Gene Regulation, Epigenetics …, 2017 - Wiley Online Library
… These factors bind to the modified his tones via specific protein interaction domains such as
the … DNA binding motifs with a preference for A/T-rich regions Methyl-CpG binding domain …

[HTML][HTML] Aryl hydrocarbon receptor as a DNA methylation reader in the stress response pathway

W Habano, T Miura, J Terashima, S Ozawa - Toxicology, 2022 - Elsevier
… readers, such as methyl-CpG-binding protein 2, which binds … to changes in the methylation
patterns around the XRE sequence. … (5mC) in a CG dinucleotide (CpG). To date, four types of …

Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

S Biswas, CM Rao - European journal of pharmacology, 2018 - Elsevier
… Cytosine methylation predominantly occurs in the context of … and the N-terminal region of
variable size. Maintenance … PRMT9 contains two SAM binding motifs like PRMT7. Further, …