… tissues for internal organs to measure DNA adducts as … The results indicate that the levels
of Michael-type adduct at α… elevated in smokers (including oral cancer and healthy). (98) …

… were also detected by our group and others in human tissues including lung, tracheobronchus,
esophagus, and cardia [23,24,25]. We demonstrated for the first time the presence of HPB…

… TS-induced DRZ adducts resulted from tobacco smokers’ lung tissues by HPLC and found
… adducts are the two most abundant adducts in lung tissues of tobacco smokers [20]. These …

… DNA adduct formed in noncancerous lung tissues obtained from lung lobectomy of lung cancer
patients of tobacco smokers (n = 41) and lung tissues … Therefore, our results suggest that …

… However, there have been many studies of DNA adduct levels in lung tissue from smokers,
… adducts could result from direct acting methylating or ethylating agents in cigarette smoke, …

… In the late 19th century, widespread cigarette use resulted in a tremendous increase in lung
… [106], demonstrated the production of bulky DNA adducts in various tissues of smokers by …

… (smokers and non-smokers) to measure tissue-derived … DNA from 30 bladder cancer
patient tissues (15 smokers and … tobacco smoke carcinogens, such as NNK and BaP, induce …

… the cytotoxic potency of tobacco-derived HQs and isomeric … did not detect either DNA
adduct in human cells; thus far, our … not been reported in human bladder tissue or bladder cell …

… and cytosine result in the formation of etheno-DNA adducts … , or due to other carcinogen(s)
present in tobacco smoke such … of many types of DNA adducts in human tissues that often …

… DNA adducts in the lung, bladder, and heart tissue are the result of DNA damaging agents
derived from ECS exposure, … that lung tissues of mice exposed to TS have lower DNA-repair …