The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… functions of DNA methylation and its establishment, maintenance and erasure during mammalian
development. … into the patterning of DNA methylation during development. Finally, we …
development. … into the patterning of DNA methylation during development. Finally, we …
Role of mammalian DNA methyltransferases in development
… DNA methylation at the 5-position of cytosine (5mC) plays vital roles in mammalian development.
DNA methylation is catalyzed by DNA methyltransferases (DNMTs), and the two DNMT …
DNA methylation is catalyzed by DNA methyltransferases (DNMTs), and the two DNMT …
DNA methylation reprogramming during mammalian development
Y Zeng, T Chen - Genes, 2019 - mdpi.com
… , are usually devoid of methylation [2]. DNA methylation is essential for mammalian development
and is involved in … Aberrant DNA methylation patterns and mutations of genes encoding …
and is involved in … Aberrant DNA methylation patterns and mutations of genes encoding …
Dynamics and context-dependent roles of DNA methylation
C Ambrosi, M Manzo, T Baubec - Journal of molecular biology, 2017 - Elsevier
… DNA methylation is one of the most … important roles during mammalian development. Its
perturbation is often associated with human diseases. In mammalian genomes, DNA methylation …
perturbation is often associated with human diseases. In mammalian genomes, DNA methylation …
DNA methylation and the preservation of cell identity
O Bogdanović, R Lister - Current opinion in genetics & development, 2017 - Elsevier
… Nevertheless, targeted deposition and removal of DNA methylation by DNMTs and … roles
of DNA methylation in the establishment and maintenance of cell identity during development, …
of DNA methylation in the establishment and maintenance of cell identity during development, …
DNA methylation and DNA methyltransferases
JR Edwards, O Yarychkivska, M Boulard… - Epigenetics & …, 2017 - Springer
… DNA methylation in mammals (which has been the subject of many reviews), we present a
new analysis of the distribution of methylated … genomes during mammalian development. The …
new analysis of the distribution of methylated … genomes during mammalian development. The …
DNA methylation homeostasis in human and mouse development
… Over the past few years, our understanding of the regulation of DNA methylation during
mammalian development has progressed tremendously however a number of central questions …
mammalian development has progressed tremendously however a number of central questions …
DNA methylation: a historical perspective
AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - cell.com
… role and interpretation of DNA methylation patterns remain under investigation. Here, we
review the field of DNA methylation … an emphasis on findings in mammalian systems, and point …
review the field of DNA methylation … an emphasis on findings in mammalian systems, and point …
Establishment and functions of DNA methylation in the germline
KR Stewart, L Veselovska, G Kelsey - Epigenomics, 2016 - Future Medicine
… These studies will continue to expand our understanding of mammalian development,
and will also shed light on how well murine gametogenesis and embryogenesis model these …
and will also shed light on how well murine gametogenesis and embryogenesis model these …
Recent progress towards understanding the role of DNA methylation in human placental development
… role DNA methylation plays in regulating placental gene expression across gestation are
poorly understood. We review genome-wide DNA methylation … very different DNA methylation …
poorly understood. We review genome-wide DNA methylation … very different DNA methylation …
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