[HTML][HTML] Analysis of genetics and DNA methylation in osteoarthritis: what have we learnt about the disease?
LN Reynard - Seminars in Cell & Developmental Biology, 2017 - Elsevier
… Epigenetic alterations, including DNA methylation … DNA methylation studies have taught
us about the genes and pathways involved in OA pathology. The influence of DNA methylation …
us about the genes and pathways involved in OA pathology. The influence of DNA methylation …
[HTML][HTML] DNA methylation in osteoarthritis: current status and therapeutic implications
A Miranda-Duarte - The open rheumatology journal, 2018 - ncbi.nlm.nih.gov
… DNA, and it comprises a mechanism through which gene–environment interactions could
occur. Its mechanisms include DNA methylation… state of DNA methylation studies related to OA …
occur. Its mechanisms include DNA methylation… state of DNA methylation studies related to OA …
Increased DNA methylation and reduced expression of transcription factors in human osteoarthritis cartilage
O Alvarez‐Garcia, KM Fisch… - Arthritis & …, 2016 - Wiley Online Library
… that were treated with the DNA methylation inhibitor 5-aza-20deoxycytidine (5-aza-dC). …
DNA methylation profiling revealed 929 differentially methylated sites between normal and …
DNA methylation profiling revealed 929 differentially methylated sites between normal and …
A pilot study of peripheral blood DNA methylation models as predictors of knee osteoarthritis radiographic progression: data from the Osteoarthritis Initiative (OAI)
… PBMC DNA was analyzed from baseline OAI visits in 58 future … DNA methylation was
quantified via Illumina microarrays and … Our findings suggest that PBMC DNA methylation-based …
quantified via Illumina microarrays and … Our findings suggest that PBMC DNA methylation-based …
Effect of DNA methylation on gene transcription is associated with the distribution of methylation sites across the genome in osteoarthritis
P Yi, X Xu, J Yao, B Qiu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
… subjects in the field of osteoarthritis (OA) research. DNA methylation may affect gene
transcription, … In the present study, the ChAMP methylation analysis package was used to identify …
transcription, … In the present study, the ChAMP methylation analysis package was used to identify …
Identification of DNA methylation changes associated with disease progression in subchondral bone with site-matched cartilage in knee osteoarthritis
Y Zhang, N Fukui, M Yahata, Y Katsuragawa… - Scientific Reports, 2016 - nature.com
… osteoarthritis, however, epigenetics of subchondral bone has not been extensively studied.
In this study, we examined the genome-wide DNA methylation … associated DNA methylation …
In this study, we examined the genome-wide DNA methylation … associated DNA methylation …
The methylation pattern for knee and hip osteoarthritis
Z Wu, L Shou, J Wang, T Huang, X Xu - Frontiers in Cell and …, 2020 - frontiersin.org
… the great potential roles of DNA methylation in OA. To systematically investigate the methylation
pattern in knee and hip osteoarthritis, we analyzed the methylation profiles in cartilage of …
pattern in knee and hip osteoarthritis, we analyzed the methylation profiles in cartilage of …
Combined bioinformatics analysis reveals gene expression and DNA methylation patterns in osteoarthritis
D Song, W Qi, M Lv, C Yuan… - Molecular Medicine …, 2018 - spandidos-publications.com
… Osteoarthritis (OA) is a common type of arthritis, which may cause pain and disability.
Alterations in gene expression and DNA methylation … expression and DNA methylation datasets. …
Alterations in gene expression and DNA methylation … expression and DNA methylation datasets. …
Analysis of DNA methylation in chondrocytes in rats with knee osteoarthritis
X Wang, D Tang, P Shen, H Xu, H Qiu, T Wu… - BMC Musculoskeletal …, 2017 - Springer
… DNA methylation works with histone acetylation to participate in aging. Alterations of DNA
methylation … The aim of this study is to detect DNA methylation changes in chondrocytes of rats …
methylation … The aim of this study is to detect DNA methylation changes in chondrocytes of rats …
[HTML][HTML] Genome-wide DNA methylation profile implicates potential cartilage regeneration at the late stage of knee osteoarthritis
Y Zhang, N Fukui, M Yahata, Y Katsuragawa… - Osteoarthritis and …, 2016 - Elsevier
… -wide DNA methylation profile of cartilage from three regions of tibial plateau isolated from
patients with primary knee osteoarthritis (OA), providing the first DNA methylation study that …
patients with primary knee osteoarthritis (OA), providing the first DNA methylation study that …
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