… stretches of hypermethylated DNA in CpG-dense promoter regions of the genes. We, … -based
DNA methylation analyses. We found specific DNA methylation profiles in pediatric MB …

… Increased DNA methylation at CpG islands is a common … Denatured DNA was deposited
on a positively charged … We found no differences in IDH1 or IDH2 gene expression level in MB …

… DNA methylation studies in medulloblastoma have focused on the role of tumor … DNA
methylation of developmental genes in pediatric medulloblastomas identified by denaturation …

… tumor in children, exhibits highly dysregulated DNA methylation. … Here, we detected global
5hmC levels in two independent … DNA for each sample (1 μg) was denatured by heating at 100…

… About half of the SHH α childhood medulloblastomas contain … The four subgroups identified
based on DNA methylation are … epigenetic changes impact medulloblastoma development. …

… Survival rates in children vary depending on the patient’s … have been identified in children
with medulloblastoma, WNT-… the standard conditions: initial denaturation at 95C for thirty …

… Medulloblastoma is a malignant childhood brain tumor and … Epigenetics is widely defined
as heritable alterations in gene … Our research on DNA methylation levels of MB showed that …

… DNA methylation has been explored as a potential driver, … Additionally, our study consists
primarily of medulloblastomas, … Cycle parameters were as follows: denaturation at 94 C 30 s, …

… , and it is uncertain its role in the disease development and … the basis for the identification of
target genes involved in the initiation … patterns of DNA methylation, gene expression profiles, …

… personal development and local capacity development through … glial cell tumour type found
in children and can occur at any … enzymatic digestion and heat denaturation (Leica, Tissue …