DNA methylation: an epigenetic mark of cellular memory

M Kim, J Costello - Experimental & molecular medicine, 2017 - nature.com
… This review covers DNA methylation as a form of epigenetic memory in stem cells and
cancer cells. We have organized this review into three main sections. The first section is an …

Drugging the methylome: DNA methylation and memory

AJ Kennedy, JD Sweatt - Critical reviews in biochemistry and …, 2016 - Taylor & Francis
memory formation, maintenance, and recall. This review incorporates various new findings
that DNA methylation … , suggesting that these epigenetic mechanisms are a fundamental link …

Epigenetic memory in development and disease: Unraveling the mechanism

S Thiagalingam - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2020 - Elsevier
… transcriptional factors and other epigenetic memory factors in conjunction with unique histone
modifications, non-coding RNAs and DNA methylation patterns are coordinated to control …

Hippocampal DNA methylation, epigenetic age, and spatial memory performance in young and old rats

P Chiavellini, M Lehmann… - The Journals of …, 2022 - academic.oup.com
… Here, we assessed age-related changes in DNA methylation (DNAm) landscape in the rat
hippocampus and the correlation of spatial memory with hippocampal DNAm age in 2.6- and …

Epigenetic memory in response to environmental stressors

P Vineis, A Chatziioannou, VT Cunliffe… - The FASEB …, 2017 - Wiley Online Library
… Below, we describe case studies used to test whether DNA methylation memories could
be created by combinations of metabolic deficiencies, developmental states, and chemical …

DNA methylation and immune memory response

NN Mittelstaedt, AL Becker, DN de Freitas, RF Zanin… - Cells, 2021 - mdpi.com
… of Treg gene expression, and the demethylated status of the Treg cell-specific demethylation
region (TSDR) appears to provide the basis of such an epigenetic memory of FOXP3. …

DNA methylation: a permissive mark in memory formation and maintenance

AMM Oliveira - Learning & Memory, 2016 - learnmem.cshlp.org
… for DNA methylation and demethylation in memory encoding. … in the methylation status
of postmitotic neuronal DNA in … current views of how memories are formed and maintained. …

Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation

JAH Maier, R Möhrle, A Jeltsch - Nature communications, 2017 - nature.com
patterns in a durable but reversible manner, but have not … synthetic epigenetic memory
systems using DNA methylation … an epigenetic memory system, which uses the methylation

Epigenetic memory marks determine epiallele stability at loci targeted by de novo DNA methylation

J Li, DL Yang, H Huang, G Zhang, LI He, J Pang… - Nature Plants, 2020 - nature.com
… Here we analysed the DNA methylation patterns of Arabidopsis thaliana plants carrying a
null mutation in NRPD1, which encodes the largest subunit of Pol IV, after reintroduction of a …

Tcf4 regulates synaptic plasticity, DNA methylation, and memory function

AJ Kennedy, EJ Rahn, BS Paulukaitis, KE Savell… - Cell reports, 2016 - cell.com
… for deficits in memory and dysregulated synaptic plasticity in the hippocampus. Thus, we
would have a model to test the transcriptional and epigenetic mechanisms dysregulated by Tcf4 …