DNA methylation is an independent prognostic marker of survival in adrenocortical cancer
A Jouinot, G Assie, R Libe, M Fassnacht… - The Journal of …, 2017 - academic.oup.com
… , somatic mutations, chromosomal alterations, and DNA methylation could identify subgroups
of ACC with markedly different outcomes (7–9). DNA methylation might be involved in the …
of ACC with markedly different outcomes (7–9). DNA methylation might be involved in the …
DNA methylation profiling reveals prognostically significant groups in pediatric adrenocortical tumors: a report from the International Pediatric Adrenocortical Tumor …
… Our results indicate DNA methylation analysis can enhance current diagnostic algorithms.
A combination of methylation and histologic classification produced the strongest prediction …
A combination of methylation and histologic classification produced the strongest prediction …
DNA methylation is a comprehensive marker for pediatric adrenocortical tumors
AC Bueno, RMP da Silva, MF Stecchini… - Endocrine-Related …, 2022 - erc.bioscientifica.com
… In the present study, we aimed to analyze the DNA methylation profile of pACT samples
from a Brazilian cohort enriched with the Gp53-p.R337H mutation. We established two …
from a Brazilian cohort enriched with the Gp53-p.R337H mutation. We established two …
[HTML][HTML] Pathway implications of aberrant global methylation in adrenocortical cancer
CR Legendre, MJ Demeure, TG Whitsett, GC Gooden… - PLoS …, 2016 - journals.plos.org
… assess DNA methylation… DNA methylation changes in ACC in the past, our study is distinct
in the manner in which we describe DNA methylation/gene expression associations to identify …
in the manner in which we describe DNA methylation/gene expression associations to identify …
DNA methylation of steroidogenic enzymes in benign adrenocortical tumors: new insights in aldosterone-producing adenomas
G Di Dalmazi, L Morandi, B Rubin… - The Journal of …, 2020 - academic.oup.com
… DNA methylation of CYP11B1 seems not to be relevant in determining cortisol overproduction
in adrenal … in our study showed that adrenal incidentalomas and ACS were spread among …
in adrenal … in our study showed that adrenal incidentalomas and ACS were spread among …
[HTML][HTML] Global DNA methylation analysis identifies two discrete clusters of pheochromocytoma with distinct genomic and genetic alterations
… This study included 39 tumours and 4 normal adrenal medullas. This is the only independent
… defined by DNA methylation were validated while proposed markers of malignancy could …
… defined by DNA methylation were validated while proposed markers of malignancy could …
[HTML][HTML] Past, present and future of epigenetics in adrenocortical carcinoma
M Ettaieb, T Kerkhofs, M van Engeland, H Haak - Cancers, 2020 - mdpi.com
… DNA methylation profiling has been suggested a reliable technique to distinguish between
benign and malignant adrenocortical … between benign and malignant adrenal tumors is of the …
benign and malignant adrenocortical … between benign and malignant adrenal tumors is of the …
[HTML][HTML] Intratumor heterogeneity of prognostic DNA-based molecular markers in adrenocortical carcinoma
A Jouinot, J Lippert, M Fassnacht… - Endocrine …, 2020 - ec.bioscientifica.com
… markers measurable at the DNA level – somatic mutations, chromosome alteration profile
and targeted DNA methylation profile – by performing multiple measures for different tumor …
and targeted DNA methylation profile – by performing multiple measures for different tumor …
[HTML][HTML] HPA axis dysregulation is associated with differential methylation of CpG-sites in related genes
A Chatzittofis, ADE Boström, DM Ciuculete… - Scientific Reports, 2021 - nature.com
… DNA methylation shifts in Hypothalamic–pituitary–adrenal (… dysregulation, shifts in DNA
methylation of HPA axis related … Our findings revealed that DNA methylation shifts are involved …
methylation of HPA axis related … Our findings revealed that DNA methylation shifts are involved …
[HTML][HTML] Alterations of DNA methylation were associated with the rapid growth of cortisol-producing adrenocortical adenoma during pregnancy
C Wang, Y Sun, X Yin, R Feng, R Feng, M Xu… - Clinical …, 2021 - Springer
… and examined the genome-wide DNA methylation profiles of non-pregnant and pregnant
patients with CPA. We aimed to identify the differences in DNA methylation signatures of non-…
patients with CPA. We aimed to identify the differences in DNA methylation signatures of non-…