… , including the collection of DNA and phenotypic information … using power calculations in
software tools such as CaTS 14 … 132 and performing large-scale experimental perturbation of …

… are a clear step forward towards quantifying genetic effects, with large-scale family studies
… across 1,000 replicate trials, with the effect size estimates then pooled across trials. From …

… This approach examines the whole genome in an agnostic system for regions where DNA
… The fraction indicates the abundance of the less common variant in the pool of alleles in the …

… Genetic ancestry is estimated from DNA and provides informa… when samples are pooled
from different research sites or … these factors into large-scale genetic studies. Appropriate …

… variant detection tools with two sets of pooled whole exome … pooling strategy can thus be
a rapid and cost-effective approach for the initial screening in large-scale association studies…

… association studies and candidate region association studies. … Currently this selected
SNP pool includes about 1 000 000 … most precious reagent is the DNA sample itself. High-quality …

… One large-scale meta-analysis study in adults identified six previously unknown loci …
Meta-analysis of genome-wide association studies identifies six new loci for serum calcium. …

… technologies and bioinformatics tools allow population … large-scale population studies but
also in cases where the … , we simulated 100-kb long DNA sequence by randomly sampling …

… Analyses of genome-wide association studies (GWAS) for … for low-cost large scale rare-variant
detection makes pooled-DNA … Our recent work has demonstrated that pooled-DNA …

… multi-population pool; and a ‘… large-scale multi-ethnic epidemiological studies become more
commonplace, it will be important to have available platforms with built in trans-ethnic utility. …