… (eg, DNAH11, DNAH5) are associated with alterations in ciliary … in CF and other chronic
airway disease phenotypes in this … Six of the seven variants associated with lung function in this …

… hyperinflation increased less in DNAH5 and DNAH11 groups. RV/total lung capacity showed
a significantly … in PCD, which may be a more sensitive index of distal airway disease. …

… However, WGS failed to identify a second variant in the DNAH5 gene, and we were unable
to establish the genetic confirmation of autosomal recessive PCD. We plan to reanalyze the …

… diseases and related phenotypes. A recent GWAS reported significant association of DNAH5
variants with total lung capacity in patients with chronic obstructive pulmonary disease 41 …

… record of chronic obstructive pulmonary disease or congestive … an intronic DNAH5 variant
and the lung function measure … link between the associated locus and DNAH5 with BDR has …

… chronic obstructive airway disease … lung function, and excluding smokers from the analysis
did not significantly change the results. Finally, although DNAH5 was significantly associated …

… PCD genes which are DNAH5 and DNAAF2 (Table 1). … phenotypes, with later onset of cough
and better lung function … weight change in chronic obstructive pulmonary disease: results …

… between BMI and respiratory function indices. Bronchiectasis … [10] Similar to other studies,
DNAH5 was the most common … change in chronic obstructive pulmonary disease: results …

… clearance leads to chronic mucopurulent airway disease that … in spite of the overall high
involvement of DNAH5, none of its … that PCD lung function outcomes are related to individual …

… variations in the region may also be associated with total lung capacity in COPD subjects
(35). … DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease. …