… The PCD-associated genetic spectrum varies among … or CCDC40 exhibit worse lung
function and rapid disease progression, … The distribution of DNAH11 and DNAH5 in our study is …

… polyps, asthma, chronic obstructive pulmonary disease (COPD), … DNAH5 is located along
the length of respiratory cilia, whereas … reportedly correlated with poor lung function in CF [64]. …

… When analyzing 15 PCD-associated genes, we identified 36 DNAH11 variants, 16 DNAH5
… Clinical characteristics of patients with chronic obstructive pulmonary disease with comorbid …

… underlying the function of cilia, can be associated with poor lung function, … obstructive lung
disease in adults [72]. One study has shown that expression of PCD – related genes, DNAH5, …

… 2 of the study (DNAI1, DNAH11, and DNAH5 x2). These four positive genetic diagnoses could
… with bronchiectasis, suspected small airway disease, bronchiolitis, complicated with cystic …

… Through whole-exome analysis, we identified variants with … in DNAH5 and (c) three
homozygotes in DNAH1, DNAH5, and … DNAH5 function and related diseases are mentioned in …

… : recurrent respiratory tract infections, low lung function, and … Defective DNAH5 causes
complete or nearly complete cilia … airway, and their function is closely related to ciliary function. …

… Hyperplastic epithelium is associated with overexpression of … such as asthma and chronic
obstructive pulmonary disease (… of DNAH5 positive staining was defined as DNAH5 abnormal …

… for total lung capacity% (TLC%) and diffusing capacity of the … origin with PCD were associated
with DNAH5 and in a study by … 8383C > T stop-gain mutation in DNAH5 was a hotspot …

… as chronic obstructive pulmonary disease (COPD), non-cystic … within this disease spectrum,
NEK10 mutation is associated with … There is a progressive loss of lung function through the …