Molecular basis of pulmonary disease
DS Zander, CF Farver - Molecular Pathology, 2018 - Elsevier
… the lung is particularly important given the role of the lung in the survival of the organism. Any
impairment of lung function … Partial or complete airway obstruction can be associated with …
impairment of lung function … Partial or complete airway obstruction can be associated with …
Pharmacogenetics of pediatric asthma: current perspectives
J Perez-Garcia, A Espuela-Ortiz… - Pharmacogenomics …, 2020 - Taylor & Francis
… 5p15.2 near DNAH5, and both of them were associated with a better response to … DNAH5
have been previously associated with lung function in chronic obstructive pulmonary disease (…
have been previously associated with lung function in chronic obstructive pulmonary disease (…
Primary ciliary dyskinesia: what the general paediatrician needs to know
J Riechmann, EC Gregson, RW Morton - Paediatrics and Child Health, 2023 - Elsevier
… DNAH5, along with DNAH11, has been linked to heavy … a greater disease severity and lower
lung function (FEV 1 ) … highlighting the presence of lower airways disease and can even be …
lung function (FEV 1 ) … highlighting the presence of lower airways disease and can even be …
Motile ciliopathies
J Wallmeier, KG Nielsen, CE Kuehni… - Nature reviews Disease …, 2020 - nature.com
… European families carried DNAH5 or DNAH11 mutations, 42… , atypical chronic obstructive
pulmonary disease (COPD)) or … associated with lung function in PCD, with poor lung function …
pulmonary disease (COPD)) or … associated with lung function in PCD, with poor lung function …
Primary Ciliary Dyskinesia Patient-Specific hiPSC-Derived Airway Epithelium in Air-Liquid Interface Culture Recapitulates Disease Specific Phenotypes In Vitro
L von Schledorn, D Puertollano Martín, N Cleve… - Cells, 2023 - mdpi.com
… PCD-associated described gene NME5 [36], respectively. Our data show that mutated DNAH5
results in loss of DNAH5 … significantly reduced MCC capacity in DNAH5-mutated cultures. …
results in loss of DNAH5 … significantly reduced MCC capacity in DNAH5-mutated cultures. …
Lung function in children with primary ciliary dyskinesia
VA Ferraro, RJ Castaldo, V Tonazzo, S Zanconato… - Children, 2023 - mdpi.com
… airway disease. Moreover, we discuss studies (9 studies, see Table 2) on … associated
with a worse prognosis and others such as DNAH9, DNAH5 and DNAH11 with milder disease…
with a worse prognosis and others such as DNAH9, DNAH5 and DNAH11 with milder disease…
Cilia in Lung Development and Disease
LL Yates, HM Mitchison, CH Dean - Cilia, 2018 - taylorfrancis.com
… development of respiratory diseases, such as Chronic Obstructive Pulmonary Disease (COPD…
, and total lung capacity is often evaluated by whole body plethysmography using a sealed …
, and total lung capacity is often evaluated by whole body plethysmography using a sealed …
[HTML][HTML] Diesel exhaust particle exposure exacerbates ciliary and epithelial barrier dysfunction in the multiciliated bronchial epithelium models
E Park, BY Kim, S Lee, KH Son, J Bang… - Ecotoxicology and …, 2024 - Elsevier
… and inflammatory-related pathways. The exposure to DEPs significantly … cilium-related genes
such as acetylated α-tubulin, ARL13B, DNAH5, and … chronic obstructive pulmonary disease …
such as acetylated α-tubulin, ARL13B, DNAH5, and … chronic obstructive pulmonary disease …
Accuracy of nasal nitric oxide measurement as a diagnostic test for primary ciliary dyskinesia. A systematic review and meta-analysis
AJ Shapiro, M Josephson, M Rosenfeld… - Annals of the …, 2017 - atsjournals.org
… In total, 10,787 records were identified through a generalized search of all publications
related to PCD for use in comprehensive guidelines on PCD diagnosis. Results were not initially …
related to PCD for use in comprehensive guidelines on PCD diagnosis. Results were not initially …
[HTML][HTML] A Novel DNAH9 Gene Mutation Causing Primary Ciliary Dyskinesia With an Unusual Association of Jejunal Atresia in a Bahraini Child
HM Isa, FA Alkharsi, MY Busehail, F Haider - Cureus, 2022 - ncbi.nlm.nih.gov
… of this rare disease to be reported from Bahrain. This case report is also associated with
an … and genetic testing for DNAI1 and DNAH5 mutations are confirmatory laboratory tests [16,17]. …
an … and genetic testing for DNAI1 and DNAH5 mutations are confirmatory laboratory tests [16,17]. …