Responsive neurostimulation of the thalamus improves seizure control in idiopathic generalised epilepsy: initial case series
… One-fifth of the approximately 3.4 million people living with … -loop brain stimulation uses
programmable detection and … ) were calculated using daily detection counter data. Sensitivity, …
programmable detection and … ) were calculated using daily detection counter data. Sensitivity, …
Stimulating native seizures with neural resonance: a new approach to localize the seizure onset zone
… The next day, we tested the same pair of electrodes and … the presence of strong oscillators
in the human brain. In the well-… We found that a model constructed from two specific features of …
in the human brain. In the well-… We found that a model constructed from two specific features of …
Electrical stimulation mapping of brain function: a comparison of subdural electrodes and stereo-EEG
… This variability in functional anatomy is even more relevant in … There are two principal
modalities for intracranial EEG … This study found that repeat stimulation of the same SDE pair …
modalities for intracranial EEG … This study found that repeat stimulation of the same SDE pair …
Personalized strategies of neurostimulation: from static biomarkers to dynamic closed-loop assessment of neural function
… In fact, variations of NIBS applied to humans currently … , personalized neurostimulation
interventions have revealed … of the brain (ie, the output) to the neurostimulation inputs in a …
interventions have revealed … of the brain (ie, the output) to the neurostimulation inputs in a …
Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes
… found that most patients received stimulation between the rising phase and peak phase of
daily … In human patients implanted with intracranial electrodes, memory tasks—which rely on …
daily … In human patients implanted with intracranial electrodes, memory tasks—which rely on …
Neuromodulation-science and practice in epilepsy: vagus nerve stimulation, thalamic deep brain stimulation, and responsive neurostimulation
MS Markert, RS Fisher - Expert review of neurotherapeutics, 2019 - Taylor & Francis
… humans, the initial effects of VNS on baseline EEG or clinical seizures were subtle at best
[Citation38]. Subsequent longitudinal studies revealed … stimulations delivered each day, which …
[Citation38]. Subsequent longitudinal studies revealed … stimulations delivered each day, which …
A rational approach to understanding and evaluating responsive neurostimulation
… We aimed to quantify the accuracy of closed-loop seizure detection and … and responding
to abnormal brain activity by delivering … flags for the daily and hourly Neurostimulator History. …
to abnormal brain activity by delivering … flags for the daily and hourly Neurostimulator History. …
Managing neurostimulation for epilepsy
… 14, 70 Additionally, the number of daily stimulations far exceeds … Early detection rate
changes from a brainresponsive … intracranial EEG monitoring with a direct brain-responsive …
changes from a brainresponsive … intracranial EEG monitoring with a direct brain-responsive …
Responsive neurostimulation as a therapy for epilepsy following new-onset refractory status epilepticus: Case series and review of the literature
… to achieve seizure control at hospital day 32. MRI … and early detection settings that were
inaccurate for detecting right-… presented with FIRES in the setting of human herpesvirus 6 (HHV-6…
inaccurate for detecting right-… presented with FIRES in the setting of human herpesvirus 6 (HHV-6…
Chronic iEEG recordings and interictal spike rate reveal multiscale temporal modulations in seizure states
… patients found that seizure network evolutions do not change … (multi-day), and/or circannual
cycles in interictal features and … in ref28, and “the human research ethics committees of the …
cycles in interictal features and … in ref28, and “the human research ethics committees of the …