… for preventing Plasmodium falciparum malaria but without … trial in humans were published
in 1998, showing that TQ was … relevant hemolysis defined as an Hb decrease of ≥30% or >…

… the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) gene and Plasmodium
falciparum multidrug resistance … , a significant decline in the early responses of childhood P. …

… for uncomplicated Plasmodium falciparum malaria in virtually all … falciparum lineages within
South and Southeast Asia and … of decreasing therapeutic effectiveness, malaria cases and …

… that chloroquine-resistant parasites were still common and present in Lambaréné, Gabon but
… withdrawal there have been signs of decrease of chloroquine resistance in some areas, for …

… decline of the Army's antimalarial research programme. It was subsequently developed as a
new prophylactic against Plasmodium falciparum … ) took place in Lambaréné, Gabon, in 1999…

… Whilst malaria incidence and mortality has decreased in the … to chloroquine in areas
where chloroquineresistant P. … failed to achieve sufficiently high cure rates (92% by Day 14 …

… acquisition of drug resistance in Plasmodium falciparum is given. … responses showed a
decreased chloroquine uptake, leaving … while increasing susceptibility to mefloquine [Citation98]. …

Background Emergence of drug resistance demands novel antimalarial drugs with new
mechanisms of action. We aimed to identify effective and well tolerated doses of ganaplacide …

… inducing immune responses against Plasmodium falciparum (Pf) … -center, Phase I trial,
conducted in Lambaréné, Gabon [22]. Study … The other volunteer showed decreasing P. malariae …

… Plasmodium falciparum is responsible for the vast majority of … falciparum in Central African
Gabon showed that single … drug reactions and may also decrease the cost-effectiveness of …