[HTML][HTML] Maternal immune activation primes deficiencies in adult hippocampal neurogenesis

ACM Couch, T Berger, B Hanger… - … , Behavior, and Immunity, 2021 - Elsevier
… which the reduction of hippocampal neurogenesis in adulthood may be driven by early life
… , we hypothesised that a reduction in AHN following MIA during pregnancy might be one …

Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu

RS Eid, JA Chaiton, SE Lieblich, TS Bodnar… - Neurobiology of …, 2019 - Elsevier
… Furthermore, circulating concentrations increase dramatically during pregnancy, drop abruptly
… that parity may modulate the effects of immune signaling on hippocampal neurogenesis. …

Hippocampal adult neurogenesis: Does the immune system matter?

AS de Miranda, CJ Zhang, A Katsumoto… - Journal of the …, 2017 - Elsevier
… aging there is a significant decrease in hippocampal neurogenesis. A role for innate and
adaptive immune system in adult neurogenesis has been also reported during aging. Here, we …

A (H1N1) vaccination recruits T lymphocytes to the choroid plexus for the promotion of hippocampal neurogenesis and working memory in pregnant mice

F Qi, J Yang, Y Xia, Q Yuan, K Guo, J Zou… - … , behavior, and immunity, 2016 - Elsevier
… pathway significantly decrease hippocampal neurogenesis to … hippocampal neurogenesis
by AIV vaccination in pregnant … of IGF-1 in the hippocampus. Moreover, compared with BDNF, …

Reproduction‐Associated Hormones and Adult Hippocampal Neurogenesis

L Wan, RJ Huang, ZH Luo, J Gong, A Pan… - Neural …, 2021 - Wiley Online Library
… -associated hormones during pregnancy. We further update the … 2γ can significantly reduce
hippocampal neurogenesis and … lead to immune dysregulation and perturbed neurogenesis. …

Maternal diet before and during pregnancy modulates microglial activation and neurogenesis in the postpartum rat brain

S Xavier, A Soch, S Younesi, S Malik… - … , Behavior, and Immunity, 2021 - Elsevier
… a reduction in activated neurons in dams fed an ω3-replete diet during pregnancy compared
to rats fed chow throughout … Our data show that hippocampal neurogenesis was significantly …

Prenatal immune activation causes hippocampal synaptic deficits in the absence of overt microglia anomalies

S Giovanoli, U Weber-Stadlbauer… - … , behavior, and immunity, 2016 - Elsevier
Prenatal immune activation led to a similar reduction in … of hippocampal synaptic deficits
following prenatal immune … to impairments in postnatal hippocampal neurogenesis, which …

SARS-CoV-2 vaccination during pregnancy enhances hippocampal neurogenesis and working memory in offspring via IFN-gamma responsive microglia

F Qi, Z Yao - bioRxiv, 2024 - biorxiv.org
… adult hippocampal neurogenesis via microglial activation17 18. Brain-resident immune cells
neurogenesis 69-71 and cognitive decline 72 73. However, these data were not focused on …

Prenatal immune and endocrine modulators of offspring's brain development and cognitive functions later in life

S Schepanski, C Buss, IL Hanganu-Opatz… - … in immunology, 2018 - frontiersin.org
… , on maternal immune-endocrine adaptation to pregnancy. … altered maternal immune-endocrine
adaptation to pregnancy can … can decrease total hippocampal volume, neurogenesis and …

Prenatal activation of toll-like receptor-4 dampens adult hippocampal neurogenesis in an IL-6 dependent manner

A Mouihate - Frontiers in Cellular Neuroscience, 2016 - frontiersin.org
… was co-injected with LPS during pregnancy. Furthermore, … offspring blunted the prenatal
LPS induced decrease in newly … immune challenge with LPS may alter neurogenesis in adult …