… However, the AR function in BC is still conflicting. Although … some instances, high levels of
AR can contribute to the therapy-… Particularly, the levels of testosterone begin to decline in the …

… of AR nuclear localization by enzalutamide decreased not only androgen-mediated but also
… , AR-targeted therapies may eventually lead to a breakthrough in breast cancer treatment. …

… androgen receptor (AR) is expressed in 70–90% of the BC incidents [6], and that it plays a
crucial role in breast cancer … -knockout mice showed reduced epithelial cell proliferation and …

… growth factor receptor 2 (HER2)-expressed, (iv) normal breast-like (low expression of luminal
… -regulated genes will increase our understanding of BCa tumor pathology and lead to the …

… cohorts have shown AR to be related to ER and PR expression and to be a marker of low-grade,
well-differentiated disease. Similarly, in TNBC tumors, a number of studies have shown …

… The role of androgen and androgen receptor (AR) in breast … androgen and AR contributes
to invasion and metastasis of … expression contributed to the decrease in CD24 high /CD44 low …

… signaling of AR may help elucidate the role for PTEN in AR+ disease progression. … Additionally,
AR inhibition with enzalutamide decreases levels of phosphorylated DNA-PKcs following …

… DFS in luminal breast cancer patients but a decrease in DFS … illustrate the complex role of
the AR in breast cancer. This … progesterone levels, which they believe could have contributed …

… Another metaanalysis indicated a low risk of cancer … Activated mTOR and PKA and inactivated
FOXO1 lead to … of androgen receptor-expressing positive breast cancer. British Journal of …

… has been increasingly recognized and this may lead to … -negative breast tumors expresses
the androgen receptor (AR) … -453 breast cancer cells through reduced Rb phosphorylation; it …