… an enhanced neuronal excitability in cerebellar granule cells (… mice models through the
bidirectional manipulation of GCs’ excitability. We clearly demonstrate that less tonic inhibition by …

… we measured the tonic inhibition current from granule cells in cerebellar slices by measuring
… significant decrease in tonic inhibition current from cerebellar granule cells of GIT1 KO mice …

… are less severe, the mice are compromised in their motor … Purkinje cell simple spike activity
is slower and is more tonic … of a different mouse model in which granule cell neurogenesis is …

… granule cell layer synaptic integration in male rats and mice … cells decreases phasic and
tonic inhibition in granule cells. A, … reduces both excitatory and inhibitory inputs to granule cells, …

… interposed cerebellar nuclei reduced dystonia-like postures in these … inhibitory 61 and
excitatory 62 feedback projections to the cerebellar cortex, where they synapse on granule cells …

… , and tonic inhibition to granule cells, and thus allow Purkinje cells to regulate granule cell
… Presynaptic boutons of PCs are brightly labeled in these mice, but there is also a low level …

… -mediated tonic inhibition in the peri-infarct motor cortex of mice … a muscimol analogue)
reduced cerebellar ataxia in an animal … above and below trigger motor dysfunctions. In our model, …

… granule cells to PCs is subject to tonic GABAergic inhibition (… not only were the tonic firing
rates were reduced but also the … This may imply a reduced number of granule cells and …

… neurotransmitter spillover and accumulation, causing tonic inhibition, and favors crosstalk
… In NR2A-Cδc /ΔC mice, NMDA receptor opening probability is reduced and the threshold for …

… are mainly expressed in cerebellar granule cells, remains unclear. … alleviated MIH in mice
by acting as a PAM at cerebellar α 6 … transmission to granule cells, which then decreases PC …