Clinical ethics in the context of deep brain stimulation for movement disorders

CS Kubu, PJ Ford - Archives of Clinical Neuropsychology, 2017 - academic.oup.com
… used to treat motor symptoms of Parkinson's disease (PD); … patients with severe tremor who
met criteria for mild dementia. … a guardianship was established to protect him. Such cases are …

Dementia and subthalamic deep brain stimulation in Parkinson disease: a long-term overview

F Bove, V Fraix, F Cavallieri, E Schmitt, E Lhommée… - Neurology, 2020 - AAN Enterprises
… should be randomized, but this option is not ethically acceptable… symptoms for many years
with cognitive safety. As for the other … Pierre Pollak for patient care and for initiating the DBS …

Deep brain stimulation at end of life: clinical and ethical considerations

LR Sankary, PJ Ford, AG Machado… - Journal of Palliative …, 2020 - liebertpub.com
… in treating motor symptoms of Parkinson disease (PD), such … The patient developed
progressive dementia and entered a … enrollment, additional care needs once enrolled, and ethical

Incoming ethical issues for deep brain stimulation: When long-term treatment leads to a 'new form of the disease'

F Gilbert, M Lancelot - Journal of Medical Ethics, 2021 - jme.bmj.com
… had an increased incidence of hallucination and dementia.… practices for DBS should be
operated through the prevention … 10 years with deep brain stimulation for Parkinson's disease--…

Bilateral deep brain stimulation of the nucleus basalis of Meynert for Parkinson disease dementia: a randomized clinical trial

J Gratwicke, L Zrinzo, J Kahan, A Peters, M Beigi… - JAMA …, 2018 - jamanetwork.com
Deep brain stimulation (DBS) has established safety and efficacy in ameliorating movement
symptoms in Parkinson disease by modulating aberrant processing patterns in motor circuits…

Shaking up the debate: ensuring the ethical use of DBS intervention criteria for mid-stage Parkinson's patients

M Eijkholt, LY Cabrera, A Ramirez-Zamora… - … : Technology at the …, 2017 - Elsevier
… stage disease, as efficacy and safety of DBS have not yet … of other comorbidities, like dementia
and other non-dopaminergic … deep brain stimulation in patients with Parkinson’s disease …

[HTML][HTML] Opening the debate on deep brain stimulation for Alzheimer disease–a critical evaluation of rationale, shortcomings, and ethical justification

M Bittlinger, S Müller - BMC medical ethics, 2018 - Springer
… raise the concern that conclusions on the potential safety and … DBS has been used in more
than 100.000 patients. It is … in severe Parkinson’s disease (PD) and dementia is one of the …

Deep-brain stimulation for Parkinson's disease: current perspectives on patient selection with an emphasis on neuropsychology

AI Tröster, FA Ponce… - Journal of Parkinsonism …, 2018 - Taylor & Francis
… : its effectiveness and safety. It is increasingly clear that a third element, namely … dementia
(PDD) are lacking for obvious practical and ethical reasons, but case studies raise concern that …

[HTML][HTML] Protocol of a randomized controlled trial investigating Deep Brain Stimulation for MOtor symptoms in patients with Parkinson's disease DEmentia (DBS-MODE …

V Sisodia, B Swinnen, JM Dijk, E Verwijk… - BMC neurology, 2023 - Springer
… and safety of DBS with BMT in patients with PDD. … is becoming standard-of-care and seems
equally effective for motor … Ethics approval was provided by the medical ethics committee (…

[HTML][HTML] Views of stakeholders at risk for dementia about deep brain stimulation for cognition

E Klein, NM Daza, I Dasgupta, K MacDuffie, A Schönau… - Brain Stimulation, 2023 - Elsevier
… (MCI), AD, or Parkinson disease dementia. DBS research for … ] or the relative dearth of
animal safety and efficacy data [15]. … There is an increasing appreciation that ethical discourse …