Patterns of IgA Autoantibody Generation, Inflammatory Responses and Extracellular Matrix Metabolism in Patients with Alcohol Use Disorder

O Niemelä, A Bloigu, R Bloigu, U Nivukoski… - International Journal of …, 2023 - mdpi.com
… Recent studies in patients with IgA nephropathy have … The values of desialylated (carbohydrate-deficient)
transferrin (… capable of inducing IgA responses and nephritogenic immune …

Tubulointerstitial nephritis

R Baracco, G Kapur, TK Mattoo - Clinical Pediatric Nephrology, 2016 - api.taylorfrancis.com
Experimental evidence suggests that native renal cells can … that nephritogenic helper T cells
producing interstitial nephritis are … it may be a target antigen in previously damaged kidneys.…

[HTML][HTML] Understanding the podocyte immune responses in proteinuric kidney diseases: from pathogenesis to therapy

H Jiang, Z Shen, J Zhuang, C Lu, Y Qu, C Xu… - Frontiers in …, 2024 - frontiersin.org
… barrier and potentially promoting glomerulosclerosis (13). … focus on developing new
experimental models, screening for … fructosylation exacerbating their nephritogenic activity (125). …

Introduction to glomerular disease: Histologic classification and pathogenesis

J Feehally, J Floege - Comprehensive clinical nephrology, 2019 - books.google.com
Experimentally, immune complexes can localize in glomeruli … appears to be activated in IgA
nephropathy, DDD, and PSGN… patients infected with specific (nephritogenic strains) of group …

Immunoglobulin-Mediated Glomerulonephritis With a Membranoproliferative Pattern of Injury and Cryoglobulinemic Glomerulonephritis

S Sethi, AS De Vriese… - Comprehensive Clinical …, 2023 - books.google.com
Nephritogenic lambda light chain dimer: a unique human … The latter is consistent with
experiments in which immortalized … Genetic Basis of IgA Nephropathy Urine abnormalities …

[HTML][HTML] Prolidase deficiency causes spontaneous T cell activation and lupus-like autoimmunity

R Hodgson, TL Crockford, A Bhandari… - The Journal of …, 2023 - journals.aai.org
… of mixed BM chimeras immunized as in (D), pooled from two experiments with four mice per
… or extrinsic defect in cell clearance. However, we cannot fully exclude defective clearance by …

Update on the application of monoclonal antibody therapy in primary membranous nephropathy

L Deng, G Xu - Drugs, 2023 - Springer
… This was largely before the role of nephritogenic autoantibodies against PLA2R and other
podocyte antigens became available and paved the way for a series of observational studies …

Gut microbiota in lupus: a butterfly effect?

R Li, X Meng, B Chen, L Zhao, X Zhang - Current Rheumatology Reports, 2021 - Springer
… Molecular mimicry is deduced in both experiments based on … gnavus is confirmed to cross-react
with nephritogenic anti-dsDNA … Butyrate and propionate could promote the differentiation …

Distinct Clinical Manifestations Associated with Autoantibodies and Cytokines in Systemic Lupus Erythematosus

FK Alduraibi - 2022 - search.proquest.com
… of nephritogenic autoAbs (eg, anti-Smith and anti-RNP) and induced lupus nephritis as a
direct … It is clear that more than one pattern of immunologic defects can result in the clinical syn- …

Assessment of novel causes and investigation into the gut microbiome in cats with chronic kidney disease

S Summers - 2020 - search.proquest.com
… evaluated whether hyperinoculation of healthy adult cats with a market leading core
vaccine over a 16-week period induces renal changes consistent with interstitial nephritis. …