… Molecular structures of the putative propofol binding sites at various … To define the number
of functional propofol-binding sites … at locations outside of the putative propofol-binding sites …

… A, the α 1 β 2 γ 2 GABA A receptor is composed of two α, two β and a γ subunit(s). Two
GABA binding sites are located at the two β+/α− subunit interfaces. The scheme shows the …

… We chose propofol to test the hypothesis that agents with weak … sites are likely to exist
in all GABA A receptors. An additional complexity is that some receptors may have no well-defined …

… infer that the actions of GABA and propofol can be described … act on the GABA A receptor
through distinct binding sites. Both … in which GABA (N GABA = 2) and propofol (N propofol = 6) …

… GABA binding sites on typical synaptic αβγ GABA A receptors… identifying GABA A receptor
sites for four potent anesthetics. … Akabas to test propofol interactions in GABA A receptors [146] …

… at postsynaptic sites, GABA binding sites are located in the … binding of GABA A R PAMs to
the intersubunit binding sites in the … of a panel of propofol derivatives and structurally unrelated …

… Our goal of identifying anesthetic-binding sites in GABA A Rs has required a number of …
-, barbiturate-, and propofol-binding sites on GABA A Rs are located in homologous pockets …

… focused largely on identifying binding sites for iv anesthetics, such as propofol, etomidate, …
Our study also demonstrated a shared ISO and SEVO binding site that is located within the β…

… The GABA binding sites were located in the ECD of the receptor protein by affinity labeling …
a channel blocker, then we have defined how picrotoxin acts as a NAM to GABA and we don't …

… Neurotransmitter binding sites are located at two or more … -defined GABA B receptors (GABABRs)
are transmembrane … the liberated propofol, subsequently potentiating GABA-inhibitory …