Cell-penetrating peptide-modified gold nanoparticles for the delivery of doxorubicin to brain metastatic breast cancer

RA Morshed, ME Muroski, Q Dai… - Molecular …, 2016 - ACS Publications
… on a gold nanoparticle platform conjugated with the cell-penetrating TAT peptide and Dox to
target brain … We would also like to gratefully acknowledge support of the High Level Talent …

Biomedical applications of the peptide decorated gold nanoparticles

A Rai, L Ferreira - Critical Reviews in Biotechnology, 2021 - Taylor & Francis
peptide-gold (Au) NP conjugates in the area of drug delivery, targeting, cancer therapy, brain
… of NPs and therefore prevent the conjugated peptide to be recognized by the cell receptors. …

Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2

C Velasco-Aguirre, F Morales-Zavala… - …, 2017 - Taylor & Francis
… GNP surface (gold nanospheres and GNR), with the aim to recognize the β-… conjugated
GNRs for the first time to the peptide Angiopep-2 as a BBB shuttle to improve delivery to the brain

Development of a novel imaging agent using peptide-coated gold nanoparticles toward brain glioma stem cell marker CD133

JH Cho, AR Kim, SH Kim, SJ Lee, H Chung, MY Yoon - Acta biomaterialia, 2017 - Elsevier
… novel small peptide that specifically recognizes CD133. This … Further, the peptide was
conjugated with gold nanoparticles … and visualize the delivered efficiency at intracellular sites. …

[HTML][HTML] Nanoparticles for targeted brain drug delivery: what do we know?

RGR Pinheiro, AJ Coutinho, M Pinheiro… - International Journal of …, 2021 - mdpi.com
… in the brain, lectin conjugated nanoparticles are promising for … well recognized by the
transporters overexpressed in brain … and is testing the efficacy of gold nanocrystals in Parkinson’s …

Designing peptide nanoparticles for efficient brain delivery

A Duro-Castano, DM Leite, J Forth, Y Deng… - Advanced drug delivery …, 2020 - Elsevier
… However, shortcomings in our understanding of peptide self-assembly and blood–brain … in
engineering peptide nanocarriers for the delivery of therapeutic compounds to the brain: from …

[HTML][HTML] Transporter protein and drug-conjugated gold nanoparticles capable of bypassing the blood-brain barrier

Y Zhang, JB Walker, Z Minic, F Liu, H Goshgarian… - Scientific reports, 2016 - nature.com
… WGA is a lectin recognized by N-acetylglucosamine and … enhance intranasal delivery of
peptides to the brain through the … are chemically linked through a nanoparticle carrier, the AuNPs…

Peptide-functionalized gold nanoparticles: versatile biomaterials for diagnostic and therapeutic applications

J Zong, SL Cobb, NR Cameron - Biomaterials science, 2017 - pubs.rsc.org
… This approach could be applied to a variety of peptide recognition motifs with high … employed
streptavidin-conjugated gold nanoparticles as a multifunctional platform for the delivery of a …

The effects of gold nanoparticles functionalized with ß-amyloid specific peptides on an in vitro model of blood–brain barrier

J Ruff, S Hüwel, MJ Kogan, U Simon… - … , Biology and Medicine, 2017 - Elsevier
… the rate-determining step of drug delivery into the brain, the development of most central
nervous system drugs is halted before completion due to their poor brain permeability. The …

Peptide-conjugated ultrasmall gold nanoparticles (2 nm) for selective protein targeting

T Ruks, K Loza, M Heggen, O Prymak… - ACS Applied Bio …, 2021 - ACS Publications
… We have attached the following synthetic model peptides which contain the pTP recognition
… Of course, this variance has to be kept in mind when further calculations (like K D values or …