Accumulation of dense core vesicles in hippocampal synapses following chronic inactivity
… increase in the mean number of dense core vesicles (DCVs) … compartment of inhibitory
synapses after 2 days treatment with … To measure the distance of a DCV to the active zone area of …
synapses after 2 days treatment with … To measure the distance of a DCV to the active zone area of …
How dense core vesicles are delivered to axon terminals–a review of modeling approaches
IA Kuznetsov, AV Kuznetsov - Modeling of microscale transport in …, 2017 - Elsevier
… This duration is much shorter than the time it would take to replenish neuropeptide stores
after … This allows us to investigate whether the reduced DCV half-life can compensate for the …
after … This allows us to investigate whether the reduced DCV half-life can compensate for the …
Maintaining the active zone: Demand, supply and disposal of core active zone proteins
NE Ziv - Neuroscience Research, 2018 - Elsevier
… AZs represent spatially confined foci at which most … numbers of transport packets and/or by
reduced numbers of CAZ … phases which are very brief and followed by massive change (eg …
reduced numbers of CAZ … phases which are very brief and followed by massive change (eg …
[HTML][HTML] Coordinated bi-directional trafficking of synaptic vesicle and active zone proteins in peripheral nerves
JK Juranek, K Mukherjee, R Jahn, JY Li - Biochemical and Biophysical …, 2021 - Elsevier
… First, we followed the transport of an integral synaptic vesicle … PTVs diminishes indicating
that other mechanisms of AZ protein … We did not find any dense core vesicles in our electron …
that other mechanisms of AZ protein … We did not find any dense core vesicles in our electron …
Vertebrate presynaptic active zone assembly: a role accomplished by diverse molecular and cellular mechanisms
VI Torres, NC Inestrosa - Molecular neurobiology, 2018 - Springer
… and number of vesicles released after stimulation. Synaptic … vesicle replenishment and
the size of RRP are decreased … with no resemblance to mature synaptic vesicles [5]. Those …
the size of RRP are decreased … with no resemblance to mature synaptic vesicles [5]. Those …
Physical determinants of vesicle mobility and supply at a central synapse
… Fluorescent recovery after photobleaching in slices from … of vesicles within MFTs, suggest
vesicle mobility is reduced by the … this density into a volume fraction, we estimated the mean …
vesicle mobility is reduced by the … this density into a volume fraction, we estimated the mean …
Vesicle release site organization at synaptic active zones
… Loewi collected the fluid surrounding the heart shortly after … between the variance and the
mean of synaptic transmission and … This was paralleled by decreased AP-evoked transmission, …
mean of synaptic transmission and … This was paralleled by decreased AP-evoked transmission, …
Rab2 drives axonal transport of dense core vesicles and lysosomal organelles
… After synthesis in the endoplasmic reticulum (ER) and transit … and lysosome-related active-zone
transport vesicles. We also … normally fed larvae was substantially reduced (to one third or …
transport vesicles. We also … normally fed larvae was substantially reduced (to one third or …
[HTML][HTML] A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation
AL Neisch, TP Neufeld, TS Hays - The Journal of cell biology, 2017 - ncbi.nlm.nih.gov
… Data represent the mean and SEM of three separate … To quantify the transport defects that
follow CKA depletion, UAS-… -CKA ΔPP2A ) after CKA depletion significantly reduced the flux of …
follow CKA depletion, UAS-… -CKA ΔPP2A ) after CKA depletion significantly reduced the flux of …
The synaptic vesicle cycle revisited: new insights into the modes and mechanisms
NL Chanaday, MA Cousin, I Milosevic… - Journal of …, 2019 - Soc Neuroscience
… resting pool and fuse at the active zone, after which they may be … zone can retrieve
endocytic vesicles that rapidly fuse with … A recent study suggested that SV clusters represent an …
endocytic vesicles that rapidly fuse with … A recent study suggested that SV clusters represent an …