… with amnestic type mild cognitive impairment (aMCI) and … to detect fast changes in neuronal
firing related to shifts from … have not detected any significant alteration in patients with aMCI, …

… the feasibility of detecting signal intensity (SI) changes of the … 24 participants with AD (12
mild AD, 12 moderate AD) and 24 … of cognitive impairment to provide a more accurate diagnosis…

… as a promising target for the identification of at-risk individuals … extracellular levels of NE
[15] or variations in pupil size [16]. … odds of conversion to mild cognitive impairment [112]. We …

… cognitive load in individuals with mild cognitive impairment (… risk for AD associated with LC
dysfunction. The LC modulates … increase in pupil dilation from low to moderate cognitive loads…

… ratio could be detected between mild cognitive impairment (MCI… of AD but categorized all
patients together into one group instead… Green arrows point to areas of signal increase. Orange …

… locus coeruleus functional connectivity (LC FC) was conducted to detect early brain functional
changes … the neural substrates of CR in mild cognitive impairment (MCI) and AD (6–10). …

… 1 individual had progressed to mild cognitive impairment. … In our sensitivity analyses, we
detected a significant association … and prospective longitudinal cognitive change, we observed …

… the disease, clinically defined as Mild Cognitive Impairment (MCI) [44, … Locus coeruleus
volume and cell population changes during … discovery. Alzheimers Dement. 2017;13(3):236–46. …

… diagnosis eventually was that of normal aging changes. … old female with the neuropathological
diagnosis of brainstem-… advanced PD (with or without mild cognitive impairment (MCI)), …

… the LC, rather than noradrenergic changes in the cortex. … In addition, cognitive impairment
has been linked to reduced … MRI measures in detecting noradrenergic degeneration within the …