Effects of cyclosporine and dexamethasone on canine T cell expression of interleukin-2 and interferon-gamma

CL Fellman, TM Archer, RW Wills, AJ Mackin - Veterinary immunology and …, 2019 - Elsevier
… effects of exposure to cyclosporine and dexamethasone on T cell cytokines measured using
both … The immune-modulating effects of dexamethasone and other steroids have also been …

A review of the mechanism of action of cyclosporine A: the role of cyclosporine A in dry eye disease and recent formulation developments

LM Periman, FS Mah, PM Karpecki - Clinical Ophthalmology, 2020 - Taylor & Francis
… of action of cyclosporine A and its role in modulating ocular … of DED, cyclosporine A affects
cytokine expression and MHC … Citation61 While topical corticosteroids demonstrate effective …

Modulation of innate immunity by cyclosporine A

AM Liddicoat, EC Lavelle - Biochemical pharmacology, 2019 - Elsevier
… of surface molecules that engage with T cells and cytokine … roles, cyclosporine A reduces the
production of cytokines that can play … B) CsA reduces ROS production and NET formation in …

[PDF][PDF] … on Altered Productions of Cytokines or Chemokines from THP-1 Cell Line Following in Vitro Exposure to Cyclophosphamide, Cyclosporine, Dexamethasone, or …

M Acharya, JH Jo, A Maharjan, R Gautam… - … of Alternatives to …, 2020 - researchgate.net
… This study aims to evaluate the immunological modulations induced by four representative
immunosuppressive on THP-1 cell line. 75% cell viabilities were determined and four test …

[HTML][HTML] In vitro inhibition of NFAT5-mediated induction of CCL2 in hyperosmotic conditions by cyclosporine and dexamethasone on human HeLa-modified …

E Warcoin, C Baudouin, C Gard, F Brignole-Baudouin - PLoS One, 2016 - journals.plos.org
… , such as inflammatory cytokine production [69,70] … expression, with a stimulatory effect in
basal conditions and an inhibitory effect in HO. Another study reported that NFAT5 modulates

[HTML][HTML] The effect of clinically relevant doses of immunosuppressive drugs on human mesenchymal stem cells

E Javorkova, J Vackova, M Hajkova… - Biomedicine & …, 2018 - Elsevier
… drugs (cyclosporine A, mycophenolate mofetil, rapamycin, prednisone and dexamethasone),
… The clinical potential of MSCs depends on their ability to modulate the immune response …

Cyclosporine A promotes the therapeutic effect of mesenchymal stem cells on transplantation reaction

M Hajkova, F Jaburek, B Porubska, P Bohacova… - Clinical …, 2019 - portlandpress.com
… – the production of numerous paracrine mediators that modulate … And, conversely, MSCs
can modulate the effect of … ConA-induced production of cytokines specific to the individual T-…

Immunosuppressive medications

AC Wiseman - Clinical Journal of the American Society of …, 2016 - journals.lww.com
… immunosuppressive effects of cyclosporin A from fermentation … bind to the intracellular
glucocorticoid receptor and modulate … by corticosteroids, with only mild decreases in Ig production. …

Corticosteroid inhibits chemokines production in systemic sclerosis patients

AT Dantas, AR de Almeida, MCPD Sampaio… - Steroids, 2017 - Elsevier
… of current corticosteroids treatment on serum cytokine and … GC effects on cytokine production
from stimulated PBMCs … the effect of corticosteroids on the cytokines modulation in systemic …

Potent immunosuppressive activity of a phosphodiesterase-4 inhibitor N-acylhydrazone in models of lipopolysaccharide-induced shock and delayed-type …

ET Guimarães, TB Dos Santos, DKC Silva… - International …, 2018 - Elsevier
… (NSAIDs) and corticosteroids have been classically used to … that observed in mice treated
with cyclosporin A at 25 mg/kg. … and modulating the secretion of proinflammatory cytokines by …